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Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue.
Clin Rev Allergy Immunol
April 2023
Rheumatology Clinic, Università Politecnica Delle Marche, Carlo Urbani" Hospital, Via Aldo Moro, 25, 60035, Jesi, Ancona, Italy.
Frailty is a new concept in rheumatology that can help identify people more likely to have less favorable outcomes. Sarcopenia and inflammaging can be regarded as the biological foundations of physical frailty. Frailty is becoming more widely accepted as an indicator of ageing and is linked to an increased risk of negative outcomes such as falls, injuries, and mortality.
View Article and Find Full Text PDFFrailty syndrome in rheumatoid arthritis and symptomatic osteoarthritis: an emerging concept in rheumatology.
Acta Biomed
May 2020
Clinica Reumatologica, Ospedale Carlo Urbani di Jesi, Università Politecnica delle Marche, (Ancona), Italy..
Musculoskeletal conditions such as rheumatoid arthritis (RA) and symptomatic osteoarthritis (OA) were the leading cause of disability in developed countries and disproportionately affects older adults. Frailty is an emerging concept in rheumatology, which represents an important construct to aid in the identification of in- dividuals who are vulnerable to adverse events and less favourable outcomes. The prevalence of frailty among the community-dwelling population increases with age: it ranges from 7% to 10% in those aged over 65 years and to 20-40% among octogenarians.
View Article and Find Full Text PDF[Octogenarian with rheumatoid arthritis, low-grade fever, severe pericardial effusion, and splenomegaly].
Rev Esp Geriatr Gerontol
April 2019
Servicio de Geriatría, Hospital General Universitario Gregorio Marañón, Madrid, España.
Total knee arthroplasty in the elderly: does age affect pain, function or complications?
Clin Orthop Relat Res
June 2013
The Western Infirmary, Glasgow, G11 6NT, UK.
Background: TKA is one of the most commonly performed procedures in the elderly, yet whether age influences postoperative pain, function, and complication rates is not fully understood for this group. This is because the current literature has limited followup, small sample sizes, and no comparator group.
Questions/purposes: We therefore asked if increasing age adversely affects postoperative pain, Knee Society Scores(©), and complication rates.
Early psoriatic arthritis.
Rheum Dis Clin North Am
May 2012
Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, 399 Bathurst Street 1E-410B, Toronto, Ontario, Canada.
Psoriatic arthritis is an inflammatory musculoskeletal disease associated with psoriasis that is usually seronegative for rheumatoid factor. Psoriatic arthritis affects men and women equally, usually during the fourth decade, although it may affect children and octogenarians. Psoriatic arthritis may lead to deformities, joint damage, reduced quality of life and function.
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