AI Article Synopsis

  • The study aimed to determine how common ectopic thyroidal thymus tissue is in children and to describe its characteristics using sonography (US).
  • Researchers reviewed US images from 216 children and found that 30 of them (approximately 13.9%) had 35 lesions that appeared to be ectopic thyroidal thymus tissue.
  • The lesions were mostly extrathyroidal (21 children) and showed specific features such as a fusiform shape, well-defined borders, and varying echo patterns, highlighting the need for radiologists to recognize these unique characteristics.

Article Abstract

Purpose: To assess the prevalence of ectopic thyroidal thymus tissue detected by sonography (US) in children and to analyze the US features.

Methods: We retrospectively reviewed images of 216 children who had undergone a thyroid or neck US examination from February 2015 to June 2015. Lesions within or adjacent to the thyroid gland that showed echopatterns consistent with thymic tissue were diagnosed as ectopic thyroidal thymus tissue. Lesions were reviewed according to their side, location, level, size, shape, echo pattern, internal content, and vascularization.

Results: A total of 216 children (119 girls, 97 boys) with a mean ± SD age of 8.6 ± 5.2 years were enrolled the study.Thirty children (13girls, 17 boys) (13.9%) had 35 lesions compatible with ectopic thyroidal thymus tissue.Nine children had intrathyroidal (4.2%) and 21 children had extrathyroidal (9.7%) ectopic thymus tissue.The mean ± SD ages of the children with and without ectopic thyroidal thymus tissue were 6.0 ± 3.6 years and 9.1 ± 5.2 years, respectively (P = .002). Twenty-five of the lesions were extrathyroidal and 10 were intrathyroidal. All extrathyroidal and most (8/9) intrathyroidal ectopic thymuses had fusiform shape with well demarcated contours. Ectopic thymuses were located either in the midportion (n = 23) or lower portion of the neck (n = 12). Both extrathyroidal and intrathyroidal ectopic thymuses showed typical hypoechoic (n = 22/25, n = 9/10, respectively) or hyperechoic (n = 3/25, n = 1/10, respectively) echo patterns with internal linear and punctate echoes.

Conclusions: Ectopic thyroidal thymic tissue is common in children. Radiologists should be vigilant about the unique US features of ectopic thyroidal thymus, including a hypo- and hyper-echoic echo pattern with multiple linear and punctate echoes, a fusiform shape, well-demarcated contours, and middle or low-lying location to differentiate it from other neck or thyroid lesions.

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcu.22590DOI Listing

Publication Analysis

Top Keywords

ectopic thyroidal
28
thyroidal thymus
24
thymus tissue
12
ectopic thymuses
12
ectopic
11
children
9
features ectopic
8
216 children
8
thymic tissue
8
echo pattern
8

Similar Publications

Ectopic thyroid tissue in the airway: a case report.

BMC Pulm Med

January 2025

Department of Respiratory Medicine, The Second Hospital of Jilin University, No. 4026 Yatai street, Changchun, 130041, Jilin, China.

Background: Ectopic thyroid tissue (ETT) is a rare congenital anomaly caused by the abnormal embryonic migration of thyroid tissue, leading to its presence outside its usual pretracheal location. This condition can lead to diagnostic challenges, especially when located within the airway, as it mimics other respiratory disorders such as asthma.

Case Presentation: We report the case of a 69-year-old man with endotracheal ETT presenting with severe dyspnea, and the lesion was initially suspected to be malignant.

View Article and Find Full Text PDF

Parathyroid Adenoma at the Parapharyngeal Space Detected on 99mTc-Sestamibi SPECT/CT.

Clin Nucl Med

January 2025

From the Nuclear Medicine Unit, Department of Diagnostic and Interventional Radiology, Queen Elizabeth Hospital, Hong Kong.

A 77-year-old woman was diagnosed with primary hyperparathyroidism, and initial cervical ultrasonography found no parathyroid lesion, and she was referred to the nuclear medicine unit for dual-phase 99mTc-sestamibi (MIBI) scan. The scintigraphy unveiled heterogeneous uptake patterns across bilateral thyroid lobes, corresponding to the thyroid nodules, alongside a marked focal uptake with delayed tracer washout in the right oral region. The SPECT/CT pinpointed a MIBI-avid nodule within the right parapharyngeal space, indicative of parathyroid ectopia.

View Article and Find Full Text PDF

Hyperparathyroidism-jaw tumor syndrome (HPT-JT) is a rare hereditary disorder caused by pathogenic gene variants. We report the case of a patient with HPT-JT who carried a novel germline pathogenic variant. A 27-year-old woman presented with thirst, polyuria, fatigue, constipation, and a history of fibro-osseous mandible lesions and endometrial polyps.

View Article and Find Full Text PDF

Case report: A case of lateral neck mass: ectopic thyroid carcinoma or lymph node metastasis?

Front Oncol

January 2025

Department of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, The China-Japan Union Hospital of Jilin University, Changchun, China.

Objective: To review a rare case of a lateral neck mass pathologically confirmed as an encapsulated papillary thyroid carcinoma in our center for complementing the lack of management of rare cases, and to explore the differentiation of primary ectopic thyroid carcinoma and metastatic disease in the context of the presence of malignant tumors within the situ thyroid gland.

Methods: We searched for studies on lateral neck ectopic thyroid cancer to compare and analyze it with metastatic carcinoma of the thyroid gland in terms of clinical features, imaging manifestations, pathological features at molecular level, and treatment principles.

Results: Based on available data, we concluded that the mass of this patient was consistent with metastatic lateral neck ectopic thyroid carcinoma.

View Article and Find Full Text PDF

Mandibular lateral ectopia: A rare case presentation.

Natl J Maxillofac Surg

November 2024

Department of Oral and Maxillofacial Surgery, Mamata Dental College, Khammam, Telangana, India.

Ectopic thyroid is a rare congenital anomaly that results from failure of decent from the foramen cecum to the primitive thyroid during the stage of embryogenesis. The specific prevalence ranges from 1 in 100,000-300,000 population. Development, genetics, and mutation play a role in the formation of ectopic thyroid.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!