AI Article Synopsis
- The study aimed to explore the psychological aspects and psychiatric disorders in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis who also experience psychogenic nonepileptic seizures, focusing on potential gender differences.
- 47 patients were assessed using various psychiatric tools, revealing that female patients were more likely to have a history of psychiatric treatment and earlier onset/duration of their seizures compared to male patients.
- Significant differences were found between genders in terms of psychiatric diagnoses, quality of life, levels of anxiety and depression, and coping strategies, indicating the need for tailored treatment approaches based on gender-specific profiles.
Article Abstract
Objective: The objective of this study was to investigate the psychological aspects and psychiatric disorders (PDs) in patients dually diagnosed with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS) with psychogenic nonepileptic seizures (PNES) treated in a tertiary center in order to find any gender differences in psychiatric, clinical, and sociodemographic characteristics.
Method: Psychiatric assessment was performed through the Diagnostic and Statistical Manual for Psychiatric Disorders - 5th edition (DSM-5). The Brazilian versions of the Medical Outcomes Study 36 (SF-36), Toronto Alexithymia Scale (TAS-20), Hamilton Depression Scale (HAM-D), Hamilton Anxiety Scale (HAM-A), and Ways of Coping Checklist (WCC) were applied.
Results: Of the 47 patients enrolled (25 females; 53.2%), females were significantly more likely to have a history of previous psychiatric treatment (P=0.02), family history of epilepsy (P=0.01), and family history of PD (P=0.03). They also presented earlier onset of PNES (P=0.01) and higher PNES duration (P=0.02) compared with males. Major depressive disorder (MDD) was the most frequent PD (24; 51.0%). Females presented more psychiatric diagnoses (P<0.001), more diagnoses of MDD (P<0.001), and posttraumatic stress disorder (PTSD) (P<0.001). Several differences regarding quality of life, levels of alexithymia, anxiety/depressive symptoms, and coping strategies were observed between groups.
Conclusions: There are significant gender differences in psychiatric, clinical, and sociodemographic aspects in a group of patients with TLE-MTS and PNES, as well as in quality of life, levels of alexithymia, anxiety/depressive symptoms, and coping strategies. These gender differences suggest that specific approaches might be adopted depending on the patient's gender and, consequently, their distinct psychological/psychiatric profile.
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| http://dx.doi.org/10.1016/j.yebeh.2018.02.026 | DOI Listing |
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