Regular foetal development is crucial for assuring good health status in the offspring. The quality and quantity of maternal dietary fatty acids (FAs) can affect growth. The study aimed to: (1) investigate the association of maternal/foetal lipid profiles with birth weight (BW); and (2) compare these profiles in small, appropriate, and large for gestational age (SGA, AGA, and LGA) infants. FAs were measured in erythrocyte membranes using gas chromatography analysis in 607 mother-infant pairs (316 males, 52.1%). In the quantile regression, a significant association between BW and levels of maternal linoleic acid (LA; C18:2, n-6; coefficient: 18.66; = 0.010), arachidonic acid (AA; C20:4, n-6; coefficient: 11.35; = 0.007), docosahexaenoic acid (DHA; C22:6, n-3; coefficient: 29.73; = 0.007), polyunsaturated FAs (coefficient: 8.55; = 0.001), foetal DHA (coefficient: -22.82; = 0.037), and saturated FAs (coefficient: -65.41; = 0.002) was found. Myristic (C14:0) and pentadecanoic acids (C15:0), both maternal ( = 0.000; = 0.017) and foetal ( = 0.009; = 0.002), and maternal erucic acid (C22:1, n-9; = 0.026) were found at higher levels in SGA infants as compared to AGA ones. Conversely, maternal LA, AA, and omega 6 FAs levels were higher in AGA infants ( = 0.037; = 0.003; = 0.026, respectively). Maternal and foetal polyunsaturated and omega 6 FAs levels are positively related to BW, while a lipid profile rich in saturated FAs and erucic acid may influence the risk of SGA.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946187 | PMC |
| http://dx.doi.org/10.3390/nu10040402 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of timing of antibiotic use on premature rupture of membranes and its impact on reproductive tract infection and fetal membrane cell scorching indicators.
Afr J Reprod Health
December 2024
Department of Obstetrics and Gynecology, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine,Changshu 215500, Jiang Su,China.
The study was designed to appraise the effects of early antibiotic administration on reproductive tract infections and fetal membrane cell scorching in instances of premature rupture of membranes (PROM). A total of 107 pregnant women diagnosed with PROM between July 2020 and June 2022 were randomly assigned to two groups: the Intervention (n=54), where ampicillin were administered within 24 hours of PROM onset, and the control group (n=53), where ampicillin were given 24-48 hours after PROM. Maternal and neonatal outcomes, incidence of reproductive tract infections, and fetal membrane cell scorching indicators (Caspase-1, Caspase -3, Caspase-9 and IL-β) were compared.
View Article and Find Full Text PDFA Statistical Model to Predict Protection Against Infant Respiratory Syncytial Virus Disease Through Maternal Immunization.
Vaccines (Basel)
November 2024
Vaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Background/objectives: Respiratory syncytial virus (RSV) is the leading cause of severe respiratory disease in infants worldwide. Maternal immunization to protect younger infants is supported by evidence that virus-neutralizing antibodies, which are efficiently transferred across the placenta from mother to fetus, are a primary immune mediator of protection. In maternal RSV vaccine studies, estimates of correlates of protection are elusive because many factors of maternal-fetal immunobiology and disease characteristics must be considered for the estimates.
View Article and Find Full Text PDFMicroplastic Particles Detected in Fetal Cord Blood, Placenta, and Meconium: A Pilot Study of Nine Mother-Infant Pairs in South China.
Toxics
November 2024
School of Public Health, Southern Medical University, No. 1023-1063, Shatai South Road, Baiyun District, Guangzhou 510515, China.
Microplastics (MPs) are emerging environmental pollutants. Pregnancy and infancy are sensitive windows for environmental exposure. However, few studies have investigated the presence of MPs in mother-infant pairs, or the exposure source.
View Article and Find Full Text PDFThe Camden Study-A Pregnancy Cohort Study of Pregnancy Complications and Birth Outcomes in Camden, New Jersey, USA.
Nutrients
December 2024
Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Background: Pregnancy is a unique stage of the life course characterized by trade-offs between the nutritional, immune, and metabolic needs of the mother and fetus. The Camden Study was originally initiated to examine nutritional status, growth, and birth outcomes in adolescent pregnancies and expanded to study dietary and molecular predictors of pregnancy complications and birth outcomes in young women.
Methods: From 1985-2006, 4765 pregnant participants aged 12 years and older were recruited from Camden, NJ, one of the poorest cities in the US.
Osteopontin Levels in Maternal Serum, Cord Blood, and Breast Milk According to Gestational Diabetes Mellitus: A Case-Control Study.
Nutrients
December 2024
Department of Social Pediatrics, Institute of Child Health, Hacettepe University, Ankara 06100, Turkey.
Background/objectives: The prevalence of gestational diabetes mellitus (GDM) is increasing, and GDM poses health risks for both mothers and newborns. This study investigated the association between GDM and two biomarkers, osteopontin (OPN) and betatrophin (ANGPTL8).
Methods: This study involved face-to-face interviews with 165 participants-81 in the GDM group and 84 in the control group-to gather maternal-newborn data.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!