Heat is a well-recognized hazard for workers in many outdoor settings, yet few investigations have compared the prevalence of outdoor work at the community level and rates of heat-related mortality and morbidity. This analysis examines whether heat-related health outcomes occur more frequently in communities with higher proportions of residents working in construction, agriculture, and other outdoor industries. Using 2005-2010 data from Los Angeles County, California, we analyze associations between community-level rates of deaths, emergency department (ED) visits, and hospitalizations during summer heat events and the prevalence of outdoor work. We find generally higher rates of heat-related ED visits and hospitalizations during summer heat events in communities with more residents working outdoors. Specifically, each percentage increase in residents working in construction resulted in an 8.1 percent increase in heat-related ED visits and a 7.9 percent increase in heat-related hospitalizations, while each percentage increase in residents working in agriculture and related sectors resulted in a 10.9 percent increase in heat-related ED visits. The findings suggest that outdoor work may significantly influence the overall burden of heat-related morbidity at the community level. Public health professionals and healthcare providers should recognize work and employment as significant heat risk factors when preparing for and responding to extreme heat events.
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http://dx.doi.org/10.3390/ijerph15040580 | DOI Listing |
Int J Mol Sci
December 2024
College of Jixian Honors, Zhejiang Agriculture and Forestry University, Hangzhou 311300, China.
Heat stress transcription factors (HSFs) play a critical role in orchestrating cellular responses to elevated temperatures and various stress conditions. While extensively studied in model plants, the gene family in remains unexplored, despite the availability of its sequenced genome. In this study, we employed bioinformatics approaches to identify 21 genes within the genome, revealing their uneven distribution across chromosomes.
View Article and Find Full Text PDFPlant Physiol Biochem
December 2024
Key Laboratory of National Forestry and Grassland Administration on Plant Conservation and Utilization in Southern China, Guangdong Provincial Key Laboratory of Applied Botany, and Xiaoliang Research Station for Tropical Coastal Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China; College of Life Sciences, Gannan Normal University, Ganzhou, 341000, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:
Heat shock transcription factor (HSF) is one of the most important regulatory elements in plant development and stress response. Rhohomyrtus tomentosa has many advantages in adapting to high temperature and high humidity climates, whereas its inherence has barely been elucidated. In this study, we aimed to characterize the HSF family and investigate the thermal adaptation mechanisms of R.
View Article and Find Full Text PDFCurr Cancer Drug Targets
January 2025
Human Genetics Laboratory, Institute of Natural Sciences, Federal University of Alfenas (UNIFAL-MG), Alfenas, 37130-001, MG, Brazil.
Histone Deacetylase 6 (HDAC6) is an intriguing therapeutic target in cancer re-search, distinguished as the only HDAC family member predominantly located in the cyto-plasm. HDAC6 features two catalytic domains and a unique ubiquitin-binding domain, which sets it apart from other HDACs. Beyond its role in histone deacetylation, HDAC6 targets vari-ous nonhistone substrates, such as α-tubulin, cortactin, Heat Shock Protein 90 (HSP90), and Heat Shock Factor 1 (HSF1).
View Article and Find Full Text PDFFront Plant Sci
December 2024
Department of Plant Sciences, College of Life Sciences, Wuhan University, Wuhan, China.
The Jacalin-related lectins () gene family play a crucial role in regulating plant development and responding to environmental stress. However, a systematic bioinformatics analysis of the gene family in Gramineae plants has been lacking. In this study, we identified 101 JRL proteins from five Gramineae species and classified them into eight distinct clades.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
January 2025
Institute of Health Equity, Chinese University of Hong Kong, Hong Kong SAR.
Background: The older population is more vulnerable to the impact of extreme hot weather events (EHWEs), while the impact on the frailer institutionalised older population was seldom assessed. Our objective was to assess the relationship between EHWEs and hospitalisation risks among institutionalised and community-dwelling older people.
Methods: We used territory-wide hospitalisation record of Hong Kong from year 2012 to 2018 to assess the associations between EHWEs and cardiovascular and respiratory disease hospitalisations in the population aged 65 or above.
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