The practicing histopathologist is often a forgotten link in the management of HIV patients. This article aims to highlight the unique challenges faced by anatomical pathologists as well as focusing on the valuable contribution they can make to ensure prompt and accurate diagnoses that will ultimately benefit the patient.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843165 | PMC |
http://dx.doi.org/10.4102/sajhivmed.v18i1.680 | DOI Listing |
Clin Exp Dermatol
January 2025
National Skin Centre, Singapore.
Historically, granulomatous inflammation has been described in association with tertiary syphilis. However, in recent years there have been increasing reports of granulomatous inflammation in patients with secondary syphilis. Here, we discuss two patients who presented with erythematous infiltrated papules and nodules and were eventually diagnosed with granulomatous secondary syphilis, with clearance of their rashes following treatment.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
March 2024
HCAI, Fungal, AMR, AMU & Sepsis Division, UKHSA, London, UK.
In 2022, there were global reports of increased numbers of acute hepatitis not explained by hepatitis A-E virus infection in children. This manuscript summarises histopathology results from 20 patients in the United Kingdom who underwent liver transplant or had a liver biopsy as part of aetiological investigations. All available histopathological samples were reviewed centrally as part of the outbreak investigation.
View Article and Find Full Text PDFCancers (Basel)
November 2023
Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of Pretoria, Pretoria 0028, South Africa.
Background: Cervical cancer prevention in regions with limited access to screening and HPV vaccination necessitates innovative approaches. This study explored the potential of a test-and-treat strategy using mRNA HPV tests to impact cervical cancer prevention in a high-prevalence HIV population.
Methods: A cervical screening study was conducted at three South African hospitals involving 710 under-screened, non-pregnant women (25 to 65 years) without known cervical diseases.
J Microsc Ultrastruct
November 2022
Department of Medicine, HIV Metabolic Clinic, Milton Keynes University Hospital NHS Foundation Trust, Eagelstone, Milton Keynes, Buckinghamshire, UK.
J Surg Res
February 2022
Department of Surgery, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng, South Africa.
Background: There has been paucity in prospective studies investigating trauma-induced changes in the cellular immunity of HIV-seropositive patients and their impact on the clinical outcome after trauma surgery. The role of natural killer (NK) cells especially has not yet been fully elucidated, and the function of this lymphocyte subtype in the immune defense after trauma is still under debate.
Methods: This prospective study included patients requiring surgery for abdominal gunshot wounds.
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