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Deciphering the Frailty Factor: Comprehensive Insights Into Its Impact on Postoperative Complications and Recovery Among Elderly Orthopedic Surgery Patients.
Indian J Orthop
February 2025
Department of Orthopaedics, Northern Railway Central Hospital, New Delhi, India.
Background: This single center-based prospective cohort study was conducted, on 157 patients over 60 years old patients requiring major orthopedic surgery, from June 2019 to June 2021. Frailty was assessed using the Edmonton Frailty Scale pre-operatively. Post-operative complications, ambulatory status, readmission rates, and mortality were monitored up to three months post-surgery, and statistical analysis was performed.
View Article and Find Full Text PDFPhysiological effects of nasal high flow therapy during exercise in patients with chronic obstructive pulmonary disease: A crossover randomised controlled trial.
Pulmonology
December 2025
Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.
Background: Nasal high flow (NHF) has been proposed to sustain high intensity exercise in people with COPD, but we have a poor understanding of its physiological effects in this clinical setting.
Research Question: What is the effect of NHF during exercise on dynamic respiratory muscle function and activation, cardiorespiratory parameters, endurance capacity, dyspnoea and leg fatigue as compared to control intervention.
Study Design And Methods: Randomized single-blind crossover trial including COPD patients.
Effect of Frailty on Postoperative Outcomes Following Major Abdominal Surgeries: A Prospective Observational Study.
Indian J Crit Care Med
November 2024
Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Background: Frailty poses unique challenges for patients undergoing major cancer surgeries due to their extreme vulnerability to physiological stressors and can be an important factor in determining postoperative outcomes.
Aims And Objective: The objective of the study was to determine the incidence of frailty in patients undergoing major abdominal cancer surgeries and identify the risk factors predicting poor outcomes.
Materials And Methods: This was a prospective observational study conducted following institutional ethics approval and CTRI registration.
Sexual dysfunction and quality of life across age groups in multiple sclerosis patients: a prospective cross-sectional analysis.
BMC Neurol
January 2025
School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Introduction: As the most frequent chronic neurological disorder in young adults, Multiple sclerosis (MS) significantly affects neurological function, particularly the autonomic nervous system. While the physical symptoms are visible, MS also causes hidden effects like sexual dysfunction. Research indicates that sexual disorders are more prevalent in MS patients compared to other neurological conditions and are approximately five times more common than in the general population.
View Article and Find Full Text PDFCauses and Outcome of Unconsciousness in the Accident and Emergency Department of the University of Port Harcourt Teaching Hospital.
Niger Med J
January 2025
Department of Accident and Emergency, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Background: Unconsciousness occurs when a patient enters a sleeplike state but cannot be aroused, and it is not due to physiological drowsiness. It is a common presentation in the Accident and Emergency Department (A&E), and a burden to the emergency physician especially when the cause is unknown. The cause of coma may be trauma or non-trauma related.
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