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Rationale and design of the HOVON 170 DLBCL-ANTICIPATE trial: preventing anthracycline-induced cardiac dysfunction with dexrazoxane.
Cardiooncology
January 2025
Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Background: Dexrazoxane has been studied for its ability to prevent anthracycline-induced cardiac dysfunction (AICD) in several trials but its use in clinical practice remains limited. This is related to the low to moderate quality of the generated evidence, safety concerns and restricted prescribing indications. Additional randomized trials are needed before this drug can be routinely integrated into cardio-oncology clinical practice.
View Article and Find Full Text PDFExploring factors of physicians' preferences for continuing medical education.
BMC Med Educ
November 2024
Faculty of Health Sciences, Bielefeld University, Bielefeld, Germany.
Background: Achieving sustainability in continuing medical education (CME) involves regular assessment of the evolving needs of healthcare professionals regarding their competencies and updates in educational content accordingly. This study aimed to investigate the key areas and competencies that physicians in Serbia prioritize for their professional development and to analyze the factors associated with these competencies.
Method: This cross-sectional study was conducted among 2,625 physicians who are members of the medical chamber in Serbia.
Using capacity assessments and tailored technical assistance to advance trauma informed care integration at the organizational level.
BMC Health Serv Res
January 2025
Cicatelli Associates Inc. (CAI), 505 8th Avenue, New York, NY, 10018, USA.
Background: The prevalence of trauma among individuals with HIV has prompted efforts to integrate trauma-informed care (TIC) into HIV care and treatment to improve health outcomes. A TIC Implementation Model, developed by a US capacity-building organization focuses on organizational changes, aligning cultural and physical environments, emphasizing values like safety and trustworthiness, engaging leadership, and training staff in skills-based TIC services. Despite growing research, gaps remain in understanding the relationship between organizational capacity, provider knowledge, and the dosage of technical assistance (TA) required to sustain TIC integration.
View Article and Find Full Text PDFCost-effectiveness analysis of extended endoscopic lumbar foraminotomy (EELF) and transforaminal lumbar interbody fusion (TLIF): a prospective observational study.
Sci Rep
January 2025
Department of Neurosurgery, Seoul National University Hospital, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Lumbar foraminal stenosis can be surgically treated by foraminal decompression or facet joint resection and fusion (transforaminal lumbar interbody fusion, TLIF). While conventional foraminal decompression poses a risk of segmental instability, the endoscopic approach (extended endoscopic lumbar foraminotomy, EELF) resects only the ventral part of the facet joint with a horizontal surgical trajectory. A prospective observational study was performed to analyze the cost-effectiveness of EELF versus TLIF.
View Article and Find Full Text PDFNeonatal outcomes in twin pregnancies in Finland from 2008 to 2023.
Eur J Pediatr
January 2025
Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Kuopio, Finland.
Unlabelled: Twin pregnancies are associated with higher risks of adverse maternal and neonatal outcomes compared to singleton pregnancies. This retrospective nationwide cohort study analyzed trends in twin pregnancy outcomes in Finland from 2008 to 2023 using data from the Finnish Medical Birth Register. Outcomes assessed included perinatal mortality, stillbirths, neonatal mortality, neonatal intensive care unit (NICU) admissions, and hospitalization rates at one week of age.
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