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Effect of Antithrombin Leakage From Hemodialysis Therapy on Antithrombin Hemodynamics.
Cureus
December 2024
Clinical Laboratory Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, JPN.
Introduction Hemodialysis (HD) therapy is a crucial treatment for patients with renal failure but can impact the hemodynamics of antithrombin (AT), a protein essential for regulating hemostasis and preventing thrombosis. Reduced AT activity can lead to thrombus formation at unusual sites and increase the risk of recurrent venous thromboembolism. The loss of AT during HD or hemodiafiltration (HDF) through leakage or adsorption onto dialysis membranes has not been fully investigated, and its effects on AT hemodynamics remain unclear.
View Article and Find Full Text PDFA Case of Bronchopneumonia Presenting With Persistent Hiccups Successfully Treated With Clonazepam and a Traditional Kampo Medicine.
Cureus
December 2024
Division of Nephrology, Toho University Sakura Medical Center, Sakura, JPN.
Persistent hiccups are rare but can serve as an early symptom of underlying conditions, including pulmonary infections and cerebrovascular disorders. This case highlights hiccups as a presenting symptom of bronchopneumonia in a hemodialysis patient and explores the effective use of chlorpromazine and Hange-koboku-to (HKT) as symptomatic therapies. Given the potential association of hiccups with neurological conditions, this case underscores the need for comprehensive diagnostic evaluation.
View Article and Find Full Text PDFHigher Processed Blood Volume of Granulocyte and Monocyte Adsorption Apheresis Ameliorates Long-Term Disease Activity in Ulcerative Colitis Patients.
J Clin Med Res
December 2024
Department of Hemodialysis and Apheresis, The University of Tokyo Hospital, Tokyo, Japan.
Background: Granulocyte and monocyte adsorption apheresis (GMA) is a therapeutic option for remission induction in the active ulcerative colitis (UC) patients. Effects of high processed blood volume of GMA as remission induction therapy on the long-term prognosis of UC patients have remained unclear. For this study, we investigated the relation between re-exacerbation of UC and the processed blood volume of GMA performed as induction therapy.
View Article and Find Full Text PDFPregnancy Related Acute Kidney Injury: An Exigent Cause of Chronic Kidney Disease in Developing Countries.
J Obstet Gynaecol India
December 2024
Department of Nephrology, SMS Medical College and Hospital, Jaipur, Rajasthan India.
Background: Development of PRAKI due to various gestation-related complication leads to poor maternal and foetal outcome. The aim of this study was to estimate the prevalence of PRAKI resulting in CKD, associated factors and feto-maternal outcome.
Methods: In this prospective observational study patients with PRAKI requiring ≥ 1 session of haemodialysis were included and followed up for 6 months to assess renal outcomes.
Leontiasis ossea in the setting of chronic kidney disease and limited dialysis access: A case report with discussion of therapeutic implications.
Radiol Case Rep
March 2025
Department of Family Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, USA.
Leontiasis ossea, also known as craniofacial fibrous dysplasia, is a rare form of osseous hypertrophy of the facial bones associated with chronic kidney disease and secondary hyperparathyroidism. As the condition progresses, changes in bone structure can lead to severe facial disfigurement, respiratory difficulties, dysarthria, and dysphagia. We describe the case of an approximately 30-year-old male with a long-standing history of end-stage renal disease who experienced rapidly progressing facial swelling and underlying bone changes following a period of poor access to dialysis.
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