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Purpose: Most bladder cancers are pure urothelial carcinomas, but a small portion, approximately 5-10%, have variant histology or are non-urothelial in nature. This research sought to examine the features of and treatment strategies for different types of urothelial carcinoma with variant histologies and non-urothelial bladder cancer.

Methods: The study cohort comprised individuals with non-urothelial and variant urothelial bladder cancers treated at two medical centres in Ankara, Turkey, between 2005 and 2024.

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Sex Disparities in Bladder Cancer Diagnosis and Treatment.

Cancers (Basel)

December 2024

Medical Oncology Unit, Centre Antoine Lacassagne, Université Côte d'Azur, 06000 Nice, France.

Article Synopsis
  • Gender differences significantly impact bladder cancer prevalence, with men at higher risk but women often diagnosed later with more advanced disease.
  • Women face more challenges with treatment outcomes and experience higher rates of recurrence after certain therapies due to differing immunogenic responses.
  • There is a pressing need for more research on sex and gender effects in bladder cancer to bridge gaps in treatment and improve prognoses for women.
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Introduction: Previously, in a randomised trial we demonstrated bipolar transurethral resection of bladder tumor (TURBT) could achieve a higher detrusor sampling rate than monopolar TURBT. We hereby report the long-term oncological outcomes following study intervention.

Methods: This is a post-hoc analysis of a randomized phase III trial comparing monopolar and bipolar TURBT.

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Background: Large cell neuroendocrine carcinoma (LCNEC) of the bladder is a rare non-urothelial tumor of the bladder. The treatment of LCNEC of the bladder is different from that of urothelial carcinoma (UC); therefore, early and accurate diagnosis is particularly important. As LCNEC of the bladder is rare and its clinical symptoms and radiographic features are similar to those of urothelial tumors, the clinical diagnosis of the disease remains challenging.

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[A real-world study of the clinical application of the Paris system for reporting urinary cytology in cancer hospital].

Zhonghua Zhong Liu Za Zhi

July 2024

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical sciences and Peking Union Medical college, Beijing 100021, China.

To evaluate the clinical value of the Paris system for reporting urinary cytology (TPS) in the diagnosis of urothelial carcinoma (UC). A total of 1 744 cytological diagnostic records (from 751 cases) were collected retrospectively. All specimens were voided urines and histopathology as the gold standard.

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