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Toxicity assessment and bioimaging potential of carbon dots synthesized from banana peel in zebrafish model.
Narra J
December 2024
Research Group of Pharmaceutics, School of Pharmacy, Institut Teknologi Bandung, Bandung, Indonesia.
Zebrafish serve as a pivotal model for bioimaging and toxicity assessments; however, the toxicity of banana peel-derived carbon dots in zebrafish has not been previously reported. The aim of this study was to assess the toxicity of carbon dots derived from banana peel in zebrafish, focusing on two types prepared through hydrothermal and pyrolysis methods. Banana peels were synthesized using hydrothermal and pyrolysis techniques and then compared for characteristics, bioimaging ability, and toxicity in zebrafish as an animal model.
View Article and Find Full Text PDFOccupational noise exposure and maternal pregnancy complications: register-based cohort from urban areas in four Nordic countries.
Occup Environ Med
January 2025
Lifestyles and Living Environments Unit, Finnish Institute for Health and Welfare, Oulu, Finland.
Objective: To assess the role of occupational noise exposure on pregnancy complications in urban Nordic populations.
Methods: A study population covering five metropolitan areas in Denmark, Finland, Norway and Sweden was generated using national birth registries linked with occupational and residential environmental exposures and sociodemographic variables. The data covered all pregnancies during 5-11 year periods in 2004‒2016, resulting in 373 184 pregnancies.
Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of four small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities.
Toxicol Sci
January 2025
National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
Several potent carcinogenic nitrosamines, including N-nitrosodiethylamine (NDEA) and N-nitrosodimethylamine (NDMA), induce micronuclei in the micronucleated hepatocyte (MNHEP) assay but not in the micronucleated reticulocyte (MNRET) assay. However, the MNHEP assay is not as frequently used as the MNRET assay for evaluating in vivo genotoxicity. The present study evaluated MN formation in the liver of Big Blue transgenic rats exposed to four small-molecule nitrosamines, NDMA, N-nitrosodiisopropylamine (NDIPA), N-nitrosoethylisoporpylamine (NEIPA), and N-nitrosomethylphenylamine (NMPA), using a repeat-dose protocol typically used for in vivo mutagenicity studies.
View Article and Find Full Text PDFCO Sequestration Technologies May Undermine China's Sustainable Development Goals through the Climate-Energy-Air-Health Cascade.
Environ Sci Technol
January 2025
College of Environmental & Resource Sciences, Zhejiang University, Hangzhou 310058, China.
CO sequestration technologies (CSTs) allow for increased CO emissions without exceeding a chosen temperature limit by creating additional carbon budgets. While these CO sequestration technologies offer low-cost routes to net-zero emissions, namely, the CST benefits, they impede progress to the Sustainable Development Goals, namely, the CST disbenefits. Focusing on China, we assess both the CST disbenefits and benefits in the climate-energy-air-health cascade by an integrated modeling framework.
View Article and Find Full Text PDF- a large-scale dataset of 3D medical shapes for computer vision.
Biomed Tech (Berl)
December 2024
Institute for Artificial Intelligence in Medicine (IKIM), University Hospital Essen (AöR), Essen, Germany.
Objectives: The shape is commonly used to describe the objects. State-of-the-art algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from the growing popularity of ShapeNet (51,300 models) and Princeton ModelNet (127,915 models).
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