Rare earths are increasingly being applied in high-tech industries, such as green energy (e.g. wind power), hybrid cars, electric cars, permanent high-performance magnets, superconductors, luminophores and many other industrial sectors involved in modern technologies. Given that China dominates this market and imposes restrictions on production and exports whenever opportunities arise, it is becoming more and more challenging to develop business ventures in this sector. Several initiatives were taken to prospect new resources and develop the production chain, including the mining of these mineral assets around the world, but some factors of uncertainties, including current low prices, increased the challenge of transforming the current resources into deposits or productive mines. Thus, analyzing the competitiveness of advanced projects becomes indispensable. This work has the objective of introducing a new methodology of competitiveness analysis, where some variables are considered as main factors that can contribute strongly to make unfeasible a mining enterprise for the use of rare earth elements (REE) with this methodology, which is quite practical and reproducible, it was possible to verify some real facts, such as: the fact that the Lynas Mount Weld CLD (AUS) Project is resilient to the uncertainties of the RE sector, at the same time as the Molycorp Project is facing major financial difficulties (under judicial reorganization). It was also possible to verify that the Araxá Project of CBMM in Brazil is one of the most competitive in this country. Thus, we contribute to the existing literature, providing a new methodology for competitiveness analysis in rare earth mining.
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http://dx.doi.org/10.1016/j.heliyon.2018.e00570 | DOI Listing |
Alzheimers Dement
December 2024
Critical Path for Alzheimer's Disease (CPAD) Consortium, Critical Path institute, Tucson, AZ, USA.
Background: To help improve the Alzheimer's disease (AD) therapeutics research and development process, the Critical Path for Alzheimer's Disease (CPAD) Consortium at the Critical Path Institute (C-Path) provides a neutral framework for the drug development industry, regulatory agencies, academia, and patient advocacy organizations to collaborate. CPAD's extensive track record of developing regulatory-grade quantitative drug development tools motivates sponsors to share patient-level data and neuroimages from clinical trials. CPAD leverages these data and uses C-Path's core competencies in data management and standardization, quantitative modeling, and regulatory science to develop tools that help de-risk decision making in AD drug development.
View Article and Find Full Text PDFGM Crops Food
December 2025
Research Center for Chinese Politics, School of Government, Peking University, Beijing, China.
As a longstanding and indispensable part of developing countries, small farmers face challenges brought by the dissemination of GM technology. Despite governments' efforts to promote collective cultivation of GM crops through top-down policies aimed at enhancing small farmers' production efficiency and market competitiveness, actual participation rates among small farmers in many developing countries remain low. This reflects a gap and mismatch between policy design and the actual needs of small farmers.
View Article and Find Full Text PDFJ Cancer
January 2025
Department of Biostatistics, School of Public Health, Harbin Medical University, Harbin 150081, China.
Platinum resistance is a common cause of chemotherapy failure in lung adenocarcinoma (LUAD). Competing endogenous RNAs (ceRNAs), which function by competitively binding to miRNAs, can influence drug response. However, the regulatory mechanisms of ceRNAs underlying chemoresistance in LUAD remain largely unknown.
View Article and Find Full Text PDFR Soc Open Sci
January 2025
Sea Mammal Research Unit, Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Fife KY16 8LB, UK.
Variation in reproductive success is a fundamental prerequisite for sexual selection to act upon a trait. Assessing such variation is crucial in understanding a species' mating system and offers insights into population growth. Parentage analyses in cetaceans are rare, and the underlying forces of sexual selection acting on their mating behaviours remain poorly understood.
View Article and Find Full Text PDFAm J Bot
January 2025
Department of Botany, University of Wisconsin-Madison, Madison, 53706, WI, USA.
Premise: Five C grasses (Bouteloua curtipendula, Schizachyrium scoparium, Andropogon gerardii, Sorghastrum nutans, Spartina pectinata) dominate different portions of a moisture gradient from dry to wet tallgrass prairies in the Upper Midwest of the United States. We hypothesized that their distributions may partly reflect differences in flooding tolerance and context-specific growth relative to each other.
Methods: We tested these ideas with greenhouse flooding and drought experiments, outdoor mesocosm experiments, and a natural experiment involving a month-long flood in two wet-mesic prairies.
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