A computational study treating cavitation phenomenon within a single bubble undergoing various controlled ultrasonic waveforms is presented in this paper. Numerical simulations using sinusoidal, square, triangular and sawtooth waves crossing an aqueous media, saturated with oxygen, are conducted upon various operational conditions of frequency and amplitude. Bubble radius, temperature and pressure were estimated over time for 64 combined cases. The obtained results show that at relatively low acoustic pressure, i.e. 1.5 and 2 atm, the square wave is proved to generate the highest temperature and pressure inside the bubble, while triangular and sawtooth ones remain the less interesting waveforms for sonochemical application within the same operational conditions. At higher amplitudes above 2.5 atm, this trend is changed, especially at low frequencies, i.e. 200 and 300 kHz, where square wave showed some limitations in attaining the optimal values of the strong collapse within one acoustic cycle.
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http://dx.doi.org/10.1016/j.ultsonch.2018.01.018 | DOI Listing |
Sci Rep
January 2025
Department of Periodontology, Peking University School and Hospital of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, No. 22 Zhongguancun South Street, Haidian District, Beijing, 100081, China.
The aim of this study was to evaluate the efficacy and patient satisfaction of lidocaine aerosol for pain management during periodontal scaling and root planning in patients with chronic periodontitis or dental plaque-induced gingivitis. This study specifically concentrated on comparing the effectiveness of lidocaine aerosol as a topical anesthetic against a placebo, assessing its impact on pain perception during the procedure. Additionally, the relationship between periodontal treatment and the reduction of oxidative stress markers in these patients was assessed.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, 03202 Elche, Alicante, Spain. Electronic address:
The biological activity of polysaccharides used for nutraceuticals/drug excipients has been a neglected area of study. This work deals with the preparation, optimization, characterization, and evaluation of persimmon (Diospyros kaki Thunb.) fruit by-products and the study of the resultant dietary fiber (DF) interaction with other compounds, using acetaminophen as a model.
View Article and Find Full Text PDFJSLS
January 2025
Department of Medical and Surgical Gynecology, Mayo Clinic College of Medicine & Science, Jacksonville, FL. (Drs. Horton, Coombs, and Cardenas-Trowers).
Background: Hysterectomy is one of the most common surgical procedures performed in the United States and most are now being performed in a minimally invasive approach. Electrosurgery and vessel sealing devices are needed in order to provide hemostasis and vascular coaptation; however, there is no guiding evidence and limited recommendations for the use of the currently available devices for laparoscopic hysterectomy. The purpose of this study is to provide a systematic review of electrosurgical devices used in benign hysterectomy and perform a meta-analysis to find the overall effect of various outcomes.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, University of Helsinki, 00014 Helsinki, Finland.
Front Bioeng Biotechnol
December 2024
Department of Medical Ultrasonics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Introduction: Effective postoperative pain management remains a significant challenge due to the severe side effects of opioids and the limitations of existing analgesic delivery systems. Inflammation plays a critical role in pain exacerbation, highlighting the need for therapies that combine analgesic effects with intrinsic anti-inflammatory properties.
Methods: Herein, we develop an intrinsic anti-inflammatory nanomedicine designed to enhance pain management by integrating controlled anesthetic release with inherent anti-inflammatory activity.
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