Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Unlabelled: Laser-assisted tympanomastoidectomy for active mucosal chronic otitis media.
Objectives: Achieving disease control in the context of active granulating mucosal chronic otitis media (COM) is typically challenging. Adjuvant laser use in cholesteatomatous COM surgery enhances disease clearance, yet its role in mucosal COM remains unexplored. The purpose of this study is to present the outcomes and our experience of the latter, and to attempt to define the role of this approach in managing mucosal COM.
Methods: Patients that underwent primary laser-assisted tympanomastoidectomy (2007-2012) for active granulating mucosal COM with at least six months follow-up were studied. Disease control was defined by successful tympanic membrane repair and resolution of otorrhoea. Time-to-event analysis using the Kaplan-Meier method was used to gain a temporal estimate of disease control.
Results: Seventy ears (66 patients) were included with mean follow-up of 22 months (6-50 months). Disease control was achieved in 94.3% of cases at latest follow-up, while one- and two-year temporal estimates of control were 97.1% and 91.8% respectively. A mean post-operative four-frequency air-bone gap of 20 dB was achieved in 52 cases (74.3%). Surgical complications included transient vertigo (n = 2), wound infection (n = 2), and temporary facial nerve palsy (n = 1).
Conclusions: We present disease control rates favourable to other published series of active mucosal COM, supporting the use of the laser as an efficacious adjunct to tympanomastoid surgery in this context. This initial report should foster further appraisal of this approach in larger prospective studies.
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