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[Hereditary protein S deficiency in a patient with prominent mesenteric venous thrombosis: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing 100191, China.
Hereditary protein S deficiency (PSD) is an autosomal dominant disorder caused by mutations in the 1 gene which can cause venous thrombosis. Individuals with PSD usually present with recurrent deep vein thrombosis and/or pulmonary embolism, but thrombosis may occur at unusual sites, such as the mesenteric and portal veins. Here we report a case of hereditary protein S deficiency patient with predominant mesenteric venous thrombosis.
View Article and Find Full Text PDFProtein-losing enteropathy as the first presentation of systemic lupus erythematosus the first case reported in Palestine with systemic review.
Ann Med Surg (Lond)
December 2024
Al- Ahli Hospital, Department of Internal Medicine, Hebron, State of Palestine.
Introduction: Systemic lupus erythematosus is a chronic inflammatory disease affecting women, causing gastrointestinal issues like acute pancreatitis, esophagitis, and protein-losing enteropathy. Protein loss is uncommon, but a case study shows protein-losing enteropathy as a first sign.
Importance: Protein-losing enteropathy (PLE) is a rare gastrointestinal manifestation of SLE, often seen years before diagnosis.
Systematic review of treatments for the gastrointestinal manifestations of systemic lupus erythematosus.
Semin Arthritis Rheum
December 2024
The University of Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia. Electronic address:
Article Synopsis
- * A thorough literature search was conducted, analyzing 29 studies involving 767 patients, focusing on various gastrointestinal problems associated with SLE and their treatments.
- * The findings indicate that while treatments like intravenous methylprednisolone and oral prednisolone may benefit patients, the overall quality of evidence is low, emphasizing the necessity for better-defined disease standards and more robust clinical trials.
Clinical features, imaging findings, and outcomes of acute abdominal pain in systemic lupus erythematosus: comparing mesenteric vasculitis, non-mesenteric vasculitis, and surgical conditions.
Clin Rheumatol
December 2024
Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Article Synopsis
- The study aimed to evaluate the clinical features and outcomes of systemic lupus erythematosus (SLE) patients who experienced acute abdominal pain (AAP), identifying them as either lupus mesenteric vasculitis (LMV), non-LMV, or surgical AAP.
- Out of 1,538 SLE patients analyzed, 62 had AAP episodes, with notable differences in symptoms and diagnostic imaging findings between the LMV group and the others, including higher rates of fever and gastrointestinal issues in LMV patients.
- The results indicated that LMV is common in SLE patients with AAP and is associated with harsher symptoms and active disease, while those with surgical AAP generally presented with localized
Quercetin ameliorates lupus symptoms by promoting the apoptosis of senescent Tfh cells via the Bcl-2 pathway.
Immun Ageing
October 2024
Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China.
Systemic lupus erythematosus (SLE) is an autoimmune disorder that commonly affects the skin, kidneys, joints, and various other systemic tissues, with its development intricately linked to the process of immunosenescence. Quercetin (QC), a phytochemical that occurs naturally, demonstrates many different biological capabilities, such as antibacterial, antioxidant, and anti-inflammatory activities. Our investigation found that QC effectively reduced kidney damage and relieved mesenteric lymph nodes (mLNs) swelling in MRL/lpr lupus mice.
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