The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 2017, were included in the databases PubMed, EBSCO, Google Scholar, and Scielo, including the terms "Tagatose", "Sweeteners", "Diabetes Mellitus type 2", "Sweeteners", "D-Tag". D-Tagatose (D-tag) is an isomer of fructose which is approximately 90% sweeter than sucrose. Preliminary studies in animals and preclinical studies showed that D-tag decreased glucose levels, which generated great interest in the scientific community. Recent studies indicate that tagatose has low glycemic index, a potent hypoglycemic effect, and eventually could be associated with important benefits for the treatment of obesity. The authors concluded that D-tag is promising as a sweetener without major adverse effects observed in these clinical studies.
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http://dx.doi.org/10.1155/2018/8718053 | DOI Listing |
Metabol Open
March 2025
School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, 92182, USA.
Background: Watermelon and its rind are rich in fiber, vitamins, minerals, and L-citrulline. Despite these nutritional benefits, research on the effects of blenderized watermelon (WM), especially in adolescents, remains limited. This study aimed to address this gap by examining the impact of blenderized WM (, including both flesh and rind) on satiety, postprandial glucose responses, and overall acceptability among overweight and obese adolescents.
View Article and Find Full Text PDFNutrients
January 2025
Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Talca 3460000, Chile.
Unlabelled: Dental caries remains a prevalent chronic disease driven by dysbiosis in the oral biofilm, with playing a central role in its pathogenesis.
Objective: This study aimed to assess the effect of D-tagatose on cariogenic risk by analyzing randomized clinical trials (RCTs).
Methods: A systematic literature review was conducted targeting RCTs published up to 2024 in eight databases and two gray literature sources.
Int J Mol Sci
January 2025
Department of Chemistry, Herbert H. Lehman College, City University of New York, New York, NY 10468, USA.
Breast cancer treatment has advanced significantly, particularly for estrogen receptor-positive (ER+) tumors. Tamoxifen, an estrogen antagonist, is widely used; however, approximately 40% of patients develop resistance. Recent studies indicate that microRNAs, especially miR-155, play a critical role in this resistance.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Department of Anatomy and Physiology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
: High fructose intake is associated with non-alcoholic fatty liver disease (NAFLD), a chronic liver disease that is on the rise worldwide. New alternatives for treatment, such as bioactive phytochemicals, are needed. The aim of this study was to investigate the beneficial role of resveratrol in treating non-alcoholic steatohepatitis (NASH).
View Article and Find Full Text PDFSheng Wu Gong Cheng Xue Bao
January 2025
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Glucose oxidase (GOD) is an oxygen-consuming dehydrogenase that can catalyze the production of gluconic acid hydrogen peroxide from glucose, and its specific mechanism of action makes it promising for applications, while the low catalytic activity and poor thermostability have become the main factors limiting the industrial application of this enzyme. In this study, we used the glucose oxidase GOD reported with the best thermostability as the source sequence for phylogenetic analysis to obtain the GOD with excellent performance. Six genes were screened and successfully synthesized for functional validation.
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