Osteonecrosis of the jaw unrelated to medication or radiotherapy.

Oral Surg Oral Med Oral Pathol Oral Radiol

Oral Surgery Department, Guys Dental Institute, Guys & St Thomas NHS Foundation Trust, Floor 23, Tower Wing, London, SE1 9RT. Electronic address:

Published: May 2018

Osteonecrosis of the jaw (ONJ) is an increasingly common condition primarily due to the rise of medication related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN). Apart from MRONJ and ORN there remains a wide and varied range of rare causes and diseases that can lead to a clinical presentation of ONJ. This article aims to highlight alternatives causes of jaw necrosis following review of the literature to aid diagnosis and treatment planning for dental and head and neck specialities.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oooo.2017.12.016DOI Listing

Publication Analysis

Top Keywords

osteonecrosis jaw
12
jaw unrelated
4
unrelated medication
4
medication radiotherapy
4
radiotherapy osteonecrosis
4
jaw onj
4
onj increasingly
4
increasingly common
4
common condition
4
condition rise
4

Similar Publications

Maxillofacial bone defects can have a profound impact on both facial function and aesthetics. While various biomaterial scaffolds have shown promise in addressing these challenges, regenerating bone in this region remains complex due to its irregular shape, intricate structure, and differing cellular origins compared to other bones in the human body. Moreover, the significant and variable mechanical loads placed on the maxillofacial bones add further complexity, especially in cases of difficult-to-treat medical conditions.

View Article and Find Full Text PDF

Clinical outcome and volumetric 3D analysis of biofluorescence imaging system guided surgery for Medication-Related Osteonecrosis of the Jaw(MRONJ).

BMC Oral Health

January 2025

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 82 Gumi-ro 173 beon-gil, Bundang-gu, Bundang‑gu, 13620, Seongnam, Republic of Korea.

Background: This study aims to evaluate the clinical outcome of biofluorescent imaging system (BIS) guided MRONJ surgery through analyzing 3D volumetric changes in CBCT data of bone structure.

Methods: BIS-guided surgery for MRONJ surgery was performed by grinding red-fluorescent area from remained residual bone detected by Qray-pen. CBCT data was collected preoperatively, postoperatively, and at last follow-up more than 3 months of each patient.

View Article and Find Full Text PDF

Using platelet concentrates to treat maxillofacial tissue lesions.

Front Bioeng Biotechnol

January 2025

State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.

Objectives: Platelet concentrates (PCs), which are blood products that are abundant in platelets and growth factors, have become pivotal in treating maxillofacial tissue lesions due to their capacity for promoting bone and soft tissue recovery. This review will provide some recent progress of the use of platelet concentrates to treat lesions on maxillofacial tissues.

Subjects: We reviewed the mechanisms by which PCs promote wound healing and tissue recovery and summarized the application of PCs in the treatment of lesions on maxillofacial tissues, including medication-related osteonecrosis of the jaw, post-extraction wound healing, implant surgery, temporomandibular joint diseases, and periodontal tissue restoration.

View Article and Find Full Text PDF

Medication related osteonecrosis (MRONJ) in the management of CTIBL in breast and prostate cancer patients. Joint report by SIPMO AND SIOMMMS.

J Bone Oncol

February 2025

Unit of Oral Medicine and Dentistry for Frail Patients, Department of Rehabilitation, Fragility, and Continuity of Care, Regional Center for Research and Care of MRONJ, University Hospital Palermo, Palermo, PA, Italy.

Background: Low-doses of bone modifying agents (LD-BMAs) compared to those used to treat bone metastases are used in breast or prostate cancer patients on adjuvant endocrine therapy to prevent Cancer Treatment Induced Bone Loss (CTIBL). Their use is associated with an increased risk of developing Medication-Related Osteonecrosis of the Jaw (MRONJ). However, there is not clarity about strategies aimed to minimize the MRONJ risk in cancer patients at different conditions as low- vs high-doses of BMA.

View Article and Find Full Text PDF

Despite the widespread use of ultrasonography (US) in medical diagnostics, there is no similar US device available for visualizing jawbone density. This study is a narrative review of the possible applications of US in dentistry. This review is divided as follows: (a) Pulse-echo ultrasonography: the applications offer new perspectives for periodontal and peri-implant assessment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!