Dispersive solid-phase imprinting of proteins for the production of plastic antibodies.

Chem Commun (Camb)

Department of Micro and Nanotechnology, Technical University of Denmark, Ørsteds Plads, DK-2800 Kgs, Lyngby, Denmark.

Published: March 2018

We describe a novel dispersive solid-phase imprinting technique for the production of nano-sized molecularly imprinted polymers (nanoMIPs) as plastic antibodies. The template was immobilized on in-house synthesized magnetic microspheres instead of conventional glass beads. As a result, high-affinity and template-free MIPs were produced in higher yields.

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http://dx.doi.org/10.1039/c8cc00343bDOI Listing

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