The wood mouse (genus ) is one of the most common rodents in broad-leaf forests in the temperate zone of the Palaearctic region. Molecular studies of wood mice have critically enhanced the understanding of their evolution and ancestral biogeographic events. However, their molecular data are currently only limited to partial mitochondrial sequences and a few genes. Therefore, we sequenced the wood mouse genome to facilitate the acquisition of useful resources for inferring their molecular evolution. We sampled a wild wood mouse at Tsukuba, Japan, and sequenced its whole-genome using the Illumina Hiseq. 2000. To reduce the risk of non-randomness, three paired-end libraries (insert sizes: 150, 300, and 500 bp) and, two mate-pair reads (insert sizes: 8 and 20 kbp) were constructed. In total, we generated approximately 210 Gbp data. From these sequences, we reconstructed 336,124 scaffolds. These data will enhance our understanding of the evolution and ecological factors that affect their genetic constitution. The genome scaffolds generated are available in the National Center Biotechnology Information (NCBI) BioProject with accession number PRJDB5914.
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http://dx.doi.org/10.1016/j.dib.2017.10.063 | DOI Listing |
Biomedicines
January 2025
Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Thiadiazine thione (THTT) has gained significant interest owing to its pharmacological potentials, particularly its antiparasitic and anti-inflammatory properties. Leishmaniasis is a clinical syndrome caused by infection with species and is associated with an inflammatory response and nociception. The available treatments against leishmaniasis are inadequate, as they are associated with high cost, toxicity, and increased resistance.
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January 2025
Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.
Categorization is an essential task for sensory perception. Individuals learn category labels using a variety of strategies to ensure that sensory signals, such as sounds or images, can be assigned to proper categories. Categories are often learned on the basis of extreme examples, and the boundary between categories can differ among individuals.
View Article and Find Full Text PDFNucleic Acids Res
January 2025
Department of Paediatrics, University of Oxford, OX3 7TY Oxford, United Kingdom.
Nucleic acid nanostructures offer unique opportunities for biomedical applications due to their sequence-programmable structures and functions, which enable the design of complex responses to molecular cues. Control of the biological activity of therapeutic cargoes based on endogenous molecular signatures holds the potential to overcome major hurdles in translational research: cell specificity and off-target effects. Endogenous microRNAs (miRNAs) can be used to profile cell type and cell state, and are ideal inputs for RNA nanodevices.
View Article and Find Full Text PDFCategorization is an essential task for sensory perception. Individuals learn category labels using a variety of strategies to ensure that sensory signals, such as sounds or images, can be assigned to proper categories. Categories are often learned on the basis of extreme examples, and the boundary between categories can differ among individuals.
View Article and Find Full Text PDFBioelectromagnetics
January 2025
Bioelectromagnetics Laboratory, University of Wollongong, Wollongong, Australia.
In this paper, we present the design, RF-EMF performance, and a comprehensive uncertainty analysis of the reverberation chamber (RC) exposure systems that have been developed for the use of researchers at the University of Wollongong Bioelectromagnetics Laboratory, Australia, for the purpose of investigating the biological effects of RF-EMF in rodents. Initial studies, at 1950 MHz, have focused on investigating thermophysiological effects of RF exposure, and replication studies related to RF-EMF exposure and progression of Alzheimer's disease (AD) in mice predisposed to AD. The RC exposure system was chosen as it allows relatively unconstrained movement of animals during exposures which can have the beneficial effect of minimizing stress-related, non-RF-induced biological and behavioral changes in the animals.
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