We report the case of a 52-year old man with no previous significant medical history presenting with progressive decrease in visual acuity (VA) of the right eye evolving over 10 years. Corrected visual acuity was 2/10 - P6 in the RE and 10/10 - P2 in the LE. The examination of the anterior segment was unremarkable. Fundus examination showed alteration of the pigment epithelium (APE) in the RE associated with osteoblast-like pigment migrations involving the macula and a wide area due to gravitational descent of the superior temporal arcade onto the lower temporal quadrant. The left eye had a similar appearance especially in the inter-papillo-macular region (A,B). Fluorescein angiography showed early hyperfluorescence areas in the PE depigmented areas associated with pigment migrations giving a comet tail appearance by gravity casting in both eyes (C,D). Optical coherence tomography (OCT) showed retrofoveolar epithelial detachment (PED) at the level of the RE (E). The patient received Diamox therapy with regular monitoring to manage possible leakage points. Patient 's evolution was marked by PED regression and VA improvement.
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http://dx.doi.org/10.11604/pamj.2017.28.182.11355 | DOI Listing |
J Binocul Vis Ocul Motil
January 2025
Eye Center, Sanno Hospital, Tokyo, Japan.
Purpose: To investigate changes in eye alignment before and after ICL implantation in patients with myopia having corrected distance visual acuity (CDVA) of ≥0.0 logMAR.
Subjects And Methods: The medical records of 1012 patients without eye movement limitation who underwent bilateral ICL implantation were retrospectively reviewed a at the Eye Center of Sanno Hospital in Japan.
Clin Ophthalmol
January 2025
Nethralayam Superspeciality Eye Care, Kolkata, India.
Purpose: To evaluate the efficacy of faricimab in real-world clinical settings in India for treating diabetic macular edema (DME) in treatment-naïve and recalcitrant eyes.
Patients And Methods: This retrospective study involved 39 eyes (16 treatment-naive and 23 recalcitrant) treated with intravitreal faricimab at four centers in India. Patients received three monthly loading doses followed by a pro-re-nata regimen, with outcomes measured for best-corrected visual acuity (BCVA), central macular thickness (CMT), intraretinal fluid (IRF), subretinal fluid (SRF), and hyperreflective foci (HRF).
Eur Heart J Open
January 2025
Department of Medicine, Cardiovascular Precision Medicine Center, Hadassah Hebrew University Medical Center, P.O. Box 12000, 9112001 Jerusalem, Israel.
Aims: Mitral valve prolapse (MVP) is a common valvular disorder associated with significant morbidity and mortality, with a strong genetic basis. This study aimed to identify a mutation in a family with MVP and to characterize the valve phenotype in LTBP2 knockout (KO) mice.
Methods And Results: Exome sequencing and segregation analysis were performed on a large family with MVP.
J Neurol Surg B Skull Base
February 2025
Department of Neurosurgery, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex (IKHC), Tehran, Iran.
In this research, the authors provide a retrospective cohort study of 82 patients with suprasellar meningiomas to identify predictors of the visual outcome following surgery. We also conducted a matched retrospective case-control analysis. This retrospective cohort study included all patients who underwent craniotomy for surgical excision of suprasellar meningiomas at our institution between January 2016 and March 2022.
View Article and Find Full Text PDFJ Neurol Surg B Skull Base
February 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Orbital apex syndrome (OAS) is characterized by visual loss, ophthalmoplegia, ptosis, and orbital pain. This study aims to analyze neuro-ophthalmologic outcomes of OAS resulting from invasive fungal rhinosinusitis (IFS). This retrospective study analyzed 25 patients diagnosed with OAS resulting from IFS between January 2018 and July 2022.
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