The original article [1] contained an error whereby Fig. 4 displayed incorrect magnification scales.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853051 | PMC |
http://dx.doi.org/10.1186/s13045-018-0587-3 | DOI Listing |
J Prev Alzheimers Dis
November 2024
Anthony O. Caggiano, MD, PhD, Cognition Therapeutics, Inc., 2500 Westchester Avenue, Purchase, NY 10577,
Background: CT1812 is a first-in-class, sigma-2 receptor ligand, that prevents and displaces binding of amyloid beta (Aβ) oligomers. Normalization of quantitative electroencephalography (qEEG) markers suggests that CT1812 protects synapses from Aβ oligomer toxicity.
Objectives: Evaluate CT1812 impact on synaptic function using qEEG measurements.
Wien Klin Wochenschr
October 2024
Department of Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.
Br J Clin Pharmacol
February 2025
Takeda Pharmaceutical Company Ltd, Cambridge, Massachusetts, USA.
Aim: This study aimed to examine the cardiac and overall safety and pharmacokinetic (PK) profiles of soticlestat (TAK-935), an oral, first-in-class selective cholesterol 24-hydroxylase inhibitor.
Methods: Data came from a randomised, phase 1 study of soticlestat in 33 healthy Japanese adults (NCT04461483); 24 adults in Part 1 (single-dose soticlestat 200-1200 mg or placebo) and 9 in Part 2 (soticlestat 100-300 mg twice daily or placebo for 21 days). PK sample collection was paired with 12-lead electrocardiogram data from continuous Holter recordings.
Ann Oncol
January 2025
Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University, Durham, USA.
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