AI Article Synopsis

  • Hospital-acquired infections (HAIs) significantly contribute to patient morbidity and mortality, prompting a study to analyze their epidemiology, clinical outcomes, and microbial profiles.
  • The research involved a prospective evaluation of 100 patients in various hospital wards who experienced 144 episodes of HAIs, identifying urine infections as the most common, particularly those caused by E. coli.
  • Findings revealed significant antibiotic resistance among the bacteria responsible for HAIs, and the study underscored the necessity for ongoing monitoring to better understand and address the prevalence of HAIs in healthcare settings.

Article Abstract

Background: Hospital-acquired infections (HAIs) are an important cause of morbidity and mortality. This study examined the epidemiology, clinical outcomes and microbiological profile of HAIs.

Methods: This prospective study was carried out on patients identified to have developed HAIs while admitted to the medical wards, surgical wards, dialysis unit and intensive care unit (ICU) of the hospital. Patients were recruited consecutively until the target study population was reached. A clinical evaluation and relevant laboratory investigations were carried out.

Results: A total of 100 patients who had 144 episodes of HAIs were studied. Rates of HAIs were 7.16%, 18.63% and 1.75% in the medical wards, ICU and surgical wards, respectively. The most common HAI was urinary tract infection caused by Escherichia coli. High-level resistance to commonly prescribed antibiotics, especially ampicillin and ceftriaxone, was observed among causative bacteria.

Conclusion: The burden of HAIs is high and similar to other parts of Nigeria. There is a need for continued surveillance of HAIs in all the wards of the hospital in order to fully describe the extent of the problem.

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Source
http://dx.doi.org/10.1093/trstmh/try020DOI Listing

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