Eye banks use sterile procedures to manipulate the eye, antiseptic measures for ocular surface decontamination, and rigorous criteria for donor selection to minimize the possibility of disease transmission due to corneal grafting. Donor selection focuses on analysis of medical records and specific post-mortem serological tests. To guide and standardize procedures, eye bank associations and government agencies provide lists of absolute and relative contraindications for use of the tissue based on donor health history. These lists are guardians of the Hippocratic principle "primum non nocere." However, each transplantation carries risk of transmission of potentially harmful agents to the recipient. The aim of the procedures is not to eliminate risk, but limit it to a reasonable level. The balance between safety and corneal availability needs to be maintained by exercising prudence without disproportionate rigor.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5935/0004-2749.20180017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Patient-reported outcome measures (PROMs) used among liver transplant recipients: a systematic review and methodological quality appraisal.
Qual Life Res
January 2025
Department of Nursing, Zhongshan Hospital of Fudan University, Shanghai, 200032, People's Republic of China.
Aim: To identify instruments used to measure patient-reported outcomes after LT, and critically evaluate their measurement properties.
Methods: Five online databases were searched to find English-language LT-specific PROMs from their inception to October 2024. Studies describing the development or validation of PROMs were included.
The 2024 American Association for Thoracic Surgery expert consensus document: Current standards in donor lung procurement and preservation.
J Thorac Cardiovasc Surg
February 2025
Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background: Donor lung procurement and preservation is critical for lung transplantation success. Unfortunately, the large variability in techniques impacts organ utilization rates and transplantation outcomes. Compounding this variation, recent developments in cold static preservation and new technological advances with machine perfusion have increased the complexity of the procedure.
View Article and Find Full Text PDFFrom chaos to order: optimizing fecal microbiota transplantation for enhanced immune checkpoint inhibitors efficacy.
Gut Microbes
December 2025
Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, Guangdong, China.
The integration of fecal microbiota transplantation (FMT) with immune checkpoint inhibitors (ICIs) presents a promising approach for enhancing cancer treatment efficacy and overcoming therapeutic resistance. This review critically examines the controversial effects of FMT on ICIs outcomes and elucidates the underlying mechanisms. We investigate how FMT modulates gut microbiota composition, microbial metabolite profiles, and the tumor microenvironment, thereby influencing ICIs effectiveness.
View Article and Find Full Text PDFUnveiling next-generation organic photovoltaics: Quantum mechanical insights into non-fullerene donor-acceptor compounds.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Chemistry, Government College University Faisalabad, Faisalabad 38000 Pakistan; Dry Lab (Janjua.XYZ), Physical Chemistry and Computational Modelling (PCCM), Department of Chemistry, Government College University Faisalabad, Faisalabad 38000 Pakistan. Electronic address:
Organic photovoltaics (OPVs) have improved greatly in recent years in pursuit for efficient and sustainable energy conversion methods. Specifically, utilizing quantum chemistry approaches such as density functional theory (DFT), the electronic structures, energy levels, and charge transport characteristics of donor-π-acceptor (D-π-A) systems based on non-fullerene donor and acceptor molecules have been examined and synthesized. Non-fullerene acceptors offer several advantages over traditional fullerene-based materials, such as enhanced light absorption, modifiable energy levels, and reduced recombination losses.
View Article and Find Full Text PDFTransfusion medicine hackathon: Nurturing the innovative ideas to revolutionize voluntary blood donation.
Asian J Transfus Sci
August 2024
Asian Association of Transfusion Medicine, India Chapter, India.
Background And Objective: Blood transfusion is an essential component of health care. However, several issues can hamper the promotion and sustainability of voluntary blood donation programs. This article is about a hackathon in the field of transfusion medicine that was designed to stimulate original ideas to promote voluntary blood donation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!