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Rapid assessment of noma: Reporting on forgotten and neglected disease in Ethiopia.
PLoS Negl Trop Dis
December 2024
Bahir Dar University, College of Medicine and Health Sciences, Bahir Dar, Ethiopia.
Background: Noma is a rapidly progressing, invasive, and debilitating orofacial disease that primarily affects the most vulnerable and marginalised populations worldwide. The highest- risk group includes pre-school children, exposed to other risk factors, such as malnutrition and poverty-related diseases. Since 2010, Ethiopia has reported an increasing number of noma cases, primarily identified through medical missions.
View Article and Find Full Text PDFClinical Diagnosis of Acute Noma: Essential Infection Markers and Clinical Presentations.
Am J Trop Med Hyg
December 2024
School of Global Health & Bioethics, Euclid University, Banjul, Gambia.
In clinical settings, understanding the markers and clinical signs of infection is critical for timely diagnosis and treatment. However, a point-of-care diagnostic test is lacking for noma, a debilitating orofacial infectious disease. This retrospective study reviewed electronic medical records (EMRs) and paper medical records (PMRs) of noma patients from Facing Africa (235 EMRs), Yekatit 12 Hospital (68 PMRs), and Project Harar (33 PMRs) in Ethiopia to identify essential infection markers and clinical presentations of acute noma.
View Article and Find Full Text PDFGastro-tracheal fistula following esophageal cancer surgery through the retrosternal route: a case report.
Surg Case Rep
November 2024
Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan.
Background: Gastro-tracheal fistula is a rare but serious complication after esophageal surgery, often requiring long-term treatment and invasive procedures. Gastro-tracheal fistula usually occurs through the posterior mediastinal route and rarely through the retrosternal route. No previous reports have described gastro-tracheal fistula after retrosternal route reconstruction was cured by conservative treatment.
View Article and Find Full Text PDFAssociation between oral health conditions and the risk of major noncommunicable diseases: A protocol for systematic review and meta-analysis.
SAGE Open Med
October 2024
Pharmacoepidemiology and Statistical Research Center, Chiang Mai University, Chiang Mai, Thailand.
Objective: Although epidemiological studies suggest that oral health conditions may be associated with an increased risk of noncommunicable diseases, the findings have yet to be comprehensively synthesized, particularly for a major noncommunicable diseases-related health and economic burden. Therefore, we will perform a systematic review and meta-analysis of all available observational studies investigating the association between oral health conditions and subsequent risk of major noncommunicable diseases.
Methods: With limited English publications, we will search electronic databases, including MEDLINE, Embase, PubMed, Cochrane Library, Scopus, and CINAHL.
Nonparametric Testing of Body Mass Index as a Predictor of Severe Noma: Assessing Potential Association.
Am J Trop Med Hyg
December 2024
School of Global Health and Bioethics, Euclid University, Banjul, The Gambia.
Noma, a devastating facial disease, primarily affects impoverished populations in low- and middle-income countries, often leading to severe disfigurement or fatality if untreated. Studies suggest malnutrition is a significant risk factor for noma, yet the association between body mass index (BMI) in kilograms per square meter and tissue damage severity remains underexplored. This study aimed to investigate the relationship between BMI and tissue damage severity among noma cases in Ethiopia.
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