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Research progress of early brain Injury in subarachnoid hemorrhage from 2004 to 2024: a bibliometric analysis.
Neurosurg Rev
January 2025
Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Early brain injury (EBI) after subarachnoid hemorrhage (SAH) is a clear correlation with poor prognosis. In the past 20 years, the research on EBI has increased rapidly. However, there is a lack of bibliometric analysis related to EBI.
View Article and Find Full Text PDFA Comparison Between Italian Division I and College American Football Players in the NFL Combine Test Battery.
J Funct Morphol Kinesiol
December 2024
Department for Life Quality Studies, University of Bologna, 40126 Bologna, Italy.
: The purpose of the present study was to evaluate the level of physical capacities of Italian American Football (AF) players and compare their performances with published data of American college players. A secondary aim was to assess whether the performance of Italian players in the NFL Combine tests has improved over time compared to previously tested players of similar competitive level. A total of 41 Italian AF players (age 28.
View Article and Find Full Text PDFSpaGraphCCI: Spatial cell-cell communication inference through GAT-based co-convolutional feature integration.
IET Syst Biol
January 2025
School of Computer, University of South China, Hengyang, Hunan, China.
Spatially resolved transcriptomics technologies potentially provide the extra spatial position information and tissue image to better infer spatial cell-cell interactions (CCIs) in processes such as tissue homeostasis, development, and disease progression. However, methods for effectively integrating spatial multimodal data to infer CCIs are still lacking. Here, the authors propose a deep learning method for integrating features through co-convolution, called SpaGraphCCI, to effectively integrate data from different modalities of SRT by projecting gene expression and image feature into a low-dimensional space.
View Article and Find Full Text PDFInflammation in atherosclerosis: a Big Idea that has underperformed so far.
Curr Opin Lipidol
January 2025
Department of Cardiovascular Sciences and Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.
Purpose Of Review: For many years, inflammation has been a major concept in basic research on atherosclerosis and in the development of potential diagnostic tools and treatments. The purpose of this review is to assess the performance of this concept with an emphasis on recent clinical trials. In addition, contemporary literature may help identify new therapeutic targets, particularly in the context of the treatment of early, rather than end-stage, arterial disease.
View Article and Find Full Text PDFStudy on Interaction Between 5-(4 Methoxyphenyl)-1-Phenyl-1H-1,2,3-Triazole with High-Abundant Blood Proteins and Identification of Low-Abundant Proteins by Serum Proteomics.
J Sep Sci
January 2025
Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, China.
A comprehensive strategy, including spectroscopic, molecular simulation, proteomics, and bioinformatics techniques, was employed to investigate a novel triazole, 5-(4-methoxyphenyl)-1-phenyl-1H-1,2,3-triazole, its interactions with high-abundance blood proteins, and identification of low-abundance proteins. The binding constants and thermodynamic parameters of the triazole to two high-abundance blood globular proteins, human serum albumin, and human immunoglobulin G (HIgG), were obtained by spectroscopic techniques and computational chemistry. The two-dimensional gel electrophoresis in combination with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was employed to isolate and identify differentially expressed low-abundance proteins in human blood serum samples following exposure to the triazole.
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