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ACS Food Sci Technol
December 2024
National Measurement Laboratory: Centre of Excellence in Agriculture and Food Integrity, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 5DL, U.K.
Salmon fillet was analyzed via hand-held optical devices: fluorescence (@340 nm) and absorption spectroscopy across the visible and near-infrared (NIR) range (400-1900 nm). Spectroscopic measurements were benchmarked with nucleotide assays and potentiometry in an exploratory set of experiments over 11 days, with changes to spectral profiles noted. A second enlarged spectroscopic data set, over a 17 day period, was then acquired, and fillet freshness was classified ±1 day via four machine learning (ML) algorithms: linear discriminant analysis, Gaussian naïve, weighted -nearest neighbors, and an ensemble bagged tree method.
View Article and Find Full Text PDFJIMD Rep
January 2025
Department of Pediatrics Prince Sultan Military Medical City (PSMMC) Riyadh Saudi Arabia.
Background: Classic homocystinuria (HCU) is a rare inborn metabolic disease that is generally asymptomatic at birth. If untreated, it can cause a wide range of complications including intellectual disability, lens dislocation, and thromboembolism. This study aimed to describe the natural history and the molecular findings of patients with HCU, and to assess the importance of early diagnosis.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland.
J Biochem Mol Toxicol
January 2025
Rheumatology and Immunology Department, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
To investigate the role and mechanism of triptophenolide (TRI) in resisting rheumatoid arthritis (RA). Network pharmacology analysis results suggested that TRI was related to multiple inflammation-related signaling proteins, and possessed the stable structural configuration. In animal experiments, TRI suppressed RA in mice, inhibited tissue inflammation, and improved synovial injury.
View Article and Find Full Text PDFLancet Digit Health
January 2025
Department of Pediatric Cardiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Engineering Research Center of Techniques and Instruments for Diagnosis and Treatment of Congenital Heart Disease, Ministry of Education, Shanghai, China. Electronic address:
Background: Perimembranous ventricular septal defect (PMVSD) is a prevalent congenital heart disease, presenting challenges in predicting spontaneous closure, which is crucial for therapeutic decisions. Existing models mainly rely on structured echocardiographic parameters or restricted data. This study introduces an artificial intelligence (AI)-based model, which uses natural language processing (NLP) and machine learning with the aim of improving spontaneous closure predictability in PMVSD.
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