Background: Lymphoepithelial cysts (LECs) are rare pancreatic cystic lesions. Since LECs are benign, preoperative diagnosis is important to differentiate from a cystic neoplasm and avoid unnecessary surgery. The aim of this study was to identify clinical, radiographic and cytopathologic features associated with LECs.
Methods: A retrospective review was performed of patients diagnosed with LEC between 1995 and 2017 at our hospital. Clinicopathologic and radiographic imaging features were documented.
Results: Of 29 patients with pancreatic LEC, 22 underwent surgical resection. The majority were male (n = 24) with a median age of 55 years (range, 21-74). During the evaluation, all patients underwent a CT, with endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) biopsy (n = 22) and/or MRI/MRCP (n = 11) performed in a smaller number of patients. A combination of exophytic tumor growth on imaging and the presence of specific cytomorphologic features on the EUS-FNA cytology biopsy led to the correct diagnosis of LEC and prevention of unnecessary surgery in 7 patients.
Discussion: Differentiating LECs from premalignant pancreatic cystic neoplasms remains difficult. Findings of an exophytic growth pattern of the lesion on abdominal imaging and the presence of specific cytomorphologic features in the EUS-FNA biopsy could help clinicians diagnose LEC preoperatively.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.hpb.2018.01.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Misdiagnosis of pancreatic intraductal papillary mucinous neoplasms and the challenge of mimicking lesions: imaging diagnosis and differentiation strategies.
Abdom Radiol (NY)
September 2024
Johns Hopkins Hospital, 1800 Orleans St., Baltimore, MD, 21287, USA.
Article Synopsis
- The increase in pancreatic cystic lesions (PCLs), especially intraductal papillary neoplasms (IPMNs), is largely due to more advanced imaging techniques like CT and MRI, leading to frequent incidental findings.
- Surveillance for IPMNs is crucial because of their cancer risk, but their similar appearance to benign lesions can cause diagnostic errors, which may result in unnecessary treatments and strain on healthcare resources.
- The paper focuses on differentiating IPMNs from similar lesions (like serous cystadenomas and others) by examining their imaging features and characteristics, aiming to improve diagnosis accuracy and patient care while reducing healthcare burdens.
Cytological features of a lymphoepithelial cyst of the salivary gland with application of the second edition of Milan System for Reporting Salivary Gland Cytopathology.
Mol Clin Oncol
August 2024
Department of Pathology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka 569-8686, Japan.
Article Synopsis
- Lymphoepithelial cysts (LECs) are rare, non-cancerous lumps that can form in the salivary glands and are surrounded by special tissue called lymphoid tissue.
- Diagnosing these cysts before surgery using a technique called fine-needle aspiration (FNA) can be tricky because sometimes they don’t show important cells in tests.
- A study looked at 13 patients with LECs and found that using the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) could help doctors better understand these cysts even though identifying them was tough.
A case of multicentric lymphoepithelial cysts in the pancreas.
J Gastrointest Surg
May 2024
Department of Anatomical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan. Electronic address:
Lymphoepithelial cyst(LEC)of the pancreas is a relatively rare benign cystic disease of the pancreas. In this report, we describe a case of LEC in which a malignant tumor could not be ruled out by preoperative diagnosis and surgery was performed. The patient was a 72-year-old man.
View Article and Find Full Text PDFSubgemmal neurogenous plaque: a series of six cases and a literature overview.
Oral Maxillofac Surg
June 2024
Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG, 31270-901, Brazil.
The study aims to describe six subgemmal neurogenous plaque (SNP) cases and compile the previously available data on SNP. Searches on PubMed, Web of Science, Embase, Scopus, and a two-step study selection were performed to compile data from case reports/series of SNP published in English literature. Our six patients (range 29-63 years) had SNP in the posterior lateral border of the tongue.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!