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Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur.
Curr Pain Headache Rep
January 2025
Phillip Capozzi MD Library, New York Medical College, Valhalla, NY, US.
Nutraceuticals are not regulated by the US Food and Drug Administration, so a careful literature review is essential to make clinical decisions. Riboflavin or vitamin B2 can be recommended for migraine prevention in adults, but pediatric use is not proven. Adverse events are minimal.
View Article and Find Full Text PDFGenome-Wide Genomic Analysis and Evolutionary Insights into Bovine Coronavirus Strains in Southwest China.
Vet Sci
December 2024
Guangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
The global epidemic of bovine coronavirus (BCoV) has caused enormous economic losses. The characterisation and genetic composition of endemic strains in Southwest China remain elusive. This study aimed to fill this gap by isolating three BCoV strains from this region and sequencing their whole genomes.
View Article and Find Full Text PDFStructure Diversity and Properties of Some Bola-like Natural Products.
Mar Drugs
December 2024
G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
In their shapes, molecules of some bipolar metabolites resemble the so-called bola, a hunting weapon of the South American inhabitants, consisting of two heavy balls connected to each other by a long flexible cord. Herein, we discuss the structures and properties of these natural products (bola-like compounds or bolaamphiphiles), containing two polar terminal fragments and a non-polar chain (or chains) between them, from archaea, bacteria, and marine invertebrates. Additional modifications of core compounds of this class, for example, interchain and intrachain cyclization, hydroxylation, methylation, etc.
View Article and Find Full Text PDFDiversity and Multigene Phylogeny of the Genus (Agaricales, Basidiomycota).
J Fungi (Basel)
January 2025
Systematic Biology, Department of Organismal Biology, Uppsala University, Norbyvägen 18D, 75236 Uppsala, Sweden.
is known as a northern-hemisphere-distributed genus with important economic values, especially in Western China. However, its species diversity in Asia and the phylogeny of this genus have not been critically studied. Based on worldwide sampling and multi-locus DNA sequence data (ITS, LSU, , ), the phylogeny of was reconstructed, and the species diversity in Asia was critically studied on the basis of morphology and phylogeny.
View Article and Find Full Text PDFInteraction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation.
Cells
January 2025
School of Medicine, Newgiza University (NGU), Giza 12577, Egypt.
Meis1 is a transcription factor involved in numerous functions including development and proliferation and has been previously shown to harness cell cycle progression. In this study, we used in silico analysis to predict that miR-499-5p targets Meis1 and that Malat1 sponges miR-499-5p. For the first time, we demonstrated that the overexpression of miR-499-5p led to the downregulation of Meis1 mRNA and protein in C166 cells by directly binding to its 3'UTR.
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