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Distinctive role of mutations in distant metastatic thyroid cancer.
Chin J Cancer Res
December 2024
Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Objective: This study investigated the clinical significance of mutations in patients with distant metastatic follicular cell-derived thyroid cancer (FDTC).
Methods: This study included 310 Chinese patients with distant metastatic FDTC. We analyzed the interactions between mutations and other gene alterations and compared the clinicopathological characteristics of patients with pathogenic (P) or likely pathogenic (LP) mutations (n=9), other gene alterations (n=253), and no gene alterations (n=37).
Pott's disease complicated by a large retroperitoneal tuberculous mass: A case report.
Int J Surg Case Rep
January 2025
Ibn Sina University Hospital Center, Rabat, Morocco.
Introduction And Importance: Tuberculosis (TB) remains a significant public health issue, especially in developing countries where its incidence is rising due to factors like overcrowding and immunosuppression. Among extrapulmonary TB forms, abdominal TB is common, while retroperitoneal TB is rare and often challenging to diagnose due to its similarity to other retroperitoneal tumors. Diagnosis typically requires invasive procedures such as laparoscopy or laparotomy.
View Article and Find Full Text PDFNasopharyngeal tuberculosis suspected of malignancy: A case report.
Medicine (Baltimore)
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, South Korea.
Rationale: Nasopharyngeal tuberculosis (TB), a rare form of tuberculosis outside the lungs, can affect any organ or tissue in the body. It is difficult to diagnose because of nonspecific symptoms, often leading to delayed confirmation after the initial patient visit. Clinical manifestations such as cervical lymphadenopathy and irregular mucosal surfaces can be challenging to distinguish from nasopharyngeal cancer or malignant lymphoma.
View Article and Find Full Text PDFTreatment outcomes and prognostic factors in patients with colorectal cancer and synchronous lung metastases in the conversion therapy era.
Int J Colorectal Dis
January 2025
Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Purpose: The Japanese Grade Classification based on the status of pulmonary and mesenteric nodal metastases and the presence of extrapulmonary metastases had a prognostic value in patients with colorectal lung metastases previously. Because the survival of such patients has improved in the era of conversion therapy, this classification needs to be reaudited.
Methods: This study reviewed the treatment sequences of 126 colorectal cancer patients with synchronous lung metastases between 2010 and 2022 at our hospital.
Colonic tuberculosis mimicking malignancy: a multidisciplinary medical and surgical approach.
BMJ Case Rep
January 2025
Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
Colonic tuberculosis (TB) is a rare form of extrapulmonary TB with nonspecific clinical presentations such as weight loss, abdominal pain and fever. It is often misdiagnosed, as the presentations mimic other more common diseases such as colon cancer and inflammatory bowel diseases, especially in those countries with low TB incidence. Although a combination of CT imaging, colonoscopy and histopathology forms the essential part of the diagnostic assessment, the high variability and low specificity of each investigation may delay or overlook the diagnosis.
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