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Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups. | LitMetric
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Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups.

Da-Yu Wang Shi-Huan Guo Gao-Fei Pan Xue-Qing Zhu Ya-Ru Gao Yong-Qiang Wang

Org Lett

Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science , Northwest University, Xi'an 710069 , P. R. China.

Published: April 2018

The utilization of the transient directing strategy into the direct oxidative dehydrogenative arylation of aldehydes with arenes was reported for the first time. Featured by mild reaction conditions, good functional group compatibility, and great regioselectivity, the method should find broad applications in new medicine and material development and discovery processes.

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 Source
http://dx.doi.org/10.1021/acs.orglett.8b00292DOI Listing

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