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A period prevalence study of palliative care need and provision in adult patients attending hospital-based dialysis units.
J Nephrol
January 2025
School of Nursing, Curtin University, Kent Street, Bentley, WA, 6102, Australia.
Background: Advanced chronic kidney disease is a life-limiting disease that is known to benefit from palliative care. Unmet palliative care need in patients with kidney failure is commonly reported but the level of need among patients receiving haemodialysis is unknown.
Methods: A period prevalence study of adult patients attending two hospital-based dialysis units was conducted.
An IgM Cleaving Enzyme for Clearance of Anti-Pig Xenoreactive Antibodies in a Nonhuman Primate Model.
Xenotransplantation
January 2025
Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Background: The removal of preformed antibodies with cleaving enzyme like IdeS (Imlifidase) has demonstrated therapeutic potential in organ transplantation for sensitized recipients. However, preformed xenoreactive antibodies (XAbs) against porcine glycans are predominantly IgM and considered detrimental in pig-to-human xenotransplantation.
Methods: Recombinant IceM, an endopeptidase cleaving IgM, was generated in Escherichia coli.
Background: Evaluation of the prognostic performance and clinical utility of the MammaPrint 70-gene signature in early-stage invasive lobular carcinoma (ILC) for whom such analyses in a randomized trial is awaited.
Patients And Methods: Exploratory subgroup analysis of MINDACT trial patients with centrally assessed histology (n = 5929) with invasive breast cancer of no-special-type (NST), or pure ILC. In the trial patients were categorized based on the 70-gene signature for genomic risk and modified Adjuvant!Online for clinical risk.
Diagnostic performance and clinical outcomes of computed tomography colonography in a sick inpatient population.
Clin Imaging
January 2025
NYU Langone Health, Department of Radiology, 660 1st Ave, New York, NY 10016, United States.
Purpose: Though prior studies have proven CTC's efficacy in outpatients, its utility in the inpatient setting has not been studied. We evaluated the efficacy of a modified CTC protocol in the inpatient setting, primarily for patients awaiting organ transplantation.
Methods: This retrospective study compared a group of inpatient CTCs from 2019 to 2021 and a randomly selected, age-matched 2:1 control group of outpatient CTCs.
Morphological Variability of the Thigh Muscle Traps in an Ultrasound That Awaits Clinicians.
J Clin Med
January 2025
Department of Clinical Anatomy, Masovian Academy in Płock, 09-402 Płock, Poland.
Muscles and their tendons present a considerable diversity of morphological variations. The aim of this study was to explore variants of muscles and tendons from compartments of the thigh and to raise awareness about potential problems during ultrasound examination. This comprehensive review of the literature was created on the basis of scientific articles sourced from PubMed.
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