AI Article Synopsis

  • The study assessed glycaemic control and antihyperglycaemic treatment in patients with type 2 diabetes aged 75 and older in Catalonia, Spain.
  • Data from 4,421 elderly patients were analyzed, revealing that 58.1% had an HbA1c level below 7.0%, with a significant portion receiving various antidiabetic medications.
  • The findings suggest that while intensive glycaemic control is common, it may not be beneficial for older adults and could increase the risk of hypoglycaemia, prompting a recommendation for healthcare providers to consider reducing treatment intensity.

Article Abstract

Aim: The aim of this study was to assess glycaemic control and prescribing practices of antihyperglycaemic treatment in patients with diabetes mellitus type 2 aged 75 years or older.

Methods: We analysed data from health electronic records from 4,581 persons attended at primary healthcare centres of the Institut Català de la Salut (ICS), in the Girona Sud area of Catalonia, Spain, during 2013 and 2016. Variables such as age, gender, body mass index (BMI), diabetes duration, age at diabetes diagnosis, glycated haemoglobin (HbA1c), creatinine, glomerular filtrate rate and the albumin/creatinine ratio in urine were collected. A descriptive analysis of the study variables was done to determinate the percentage of persons on antidiabetic treatment.

Results: We identified 4,421 persons aged 75 years or older who provided data on HbA1c and antidiabetic treatment. Mean age was 82.3 (5.1) years. In 58.1% of patients, the level of HbA1c was below 7.0%, while in 36.8% it was below 6.5%. Between patients with HbA1c below 7.0%, antidiabetic drugs were taken by 70.2%, where 15.2% were either on insulin, sulphonylureas or repaglinide therapy.

Conclusion: Intensive treatment among older adults with diabetes mellitus type 2 is common in primary care clinical practice in our area. Intensive glycaemic control confers an increased risk of hypoglycaemia and little benefit among older individuals with diabetes. Physicians should take care more not to harm those populations and treatment should be de-intensified to reduce the risk of hypoglycaemia.

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http://dx.doi.org/10.1111/ijcp.13075DOI Listing

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