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CRISPR detection of cardiac tumor-associated microRNAs.
Mol Biol Rep
January 2025
Department of Cardiology, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
As multiple imaging modalities cannot reliably diagnose cardiac tumors, the molecular approach offers alternative ways to detect rare ones. One such molecular approach is CRISPR-based diagnostics (CRISPR-Dx). CRISPR-Dx enables visual readout, portable diagnostics, and rapid and multiplex detection of nucleic acids such as microRNA (miRNA).
View Article and Find Full Text PDFA surgical case of right atrial wall perforation caused by an invasive angiosarcoma.
Interdiscip Cardiovasc Thorac Surg
December 2024
Department of Cardiovascular Surgery, Yotsuba Circulation Clinic, Ehime, Japan.
Cardiac angiosarcoma is a rare, diagnostically elusive disease with a poor prognosis. Herein, we describe the case of a 61-year-old man who presented with cardiac tamponade caused by perforation of the right atrial wall resulting from an invasive angiosarcoma. The tumour, which had spread throughout the entire right atrial free wall, was resected under cardiopulmonary bypass.
View Article and Find Full Text PDFCardiac angiosarcoma: how multimodality imaging and excimer laser assisted intracardiac biopsy led to the correct diagnosis-a case report.
Eur Heart J Case Rep
December 2024
Department of Cardiology & Critical Care Medicine, Asklepios Klinik St. Georg, Lohmühlenstraße 5, 20099 Hamburg, Germany.
Background: Cardiac angiosarcomas are exceptionally uncommon, and result in significant morbidity and mortality. Utilizing a multimodality approach enhances the characterization of the mass for optimal diagnostic outcomes. The recommended primary treatment involves complete surgical resection coupled with adjuvant radiochemotherapy.
View Article and Find Full Text PDFPrimary cardiac angiosarcoma is a rare and aggressive malignant tumor with a poor clinical outcome. Its nonspecific symptoms often complicate early diagnosis. Here, we present the case of a 39-year-old man who initially presented with pericardial effusion and cardiac tamponade.
View Article and Find Full Text PDFGiant right atrial tumor following catheter ablation.
Gen Thorac Cardiovasc Surg Cases
February 2024
Department of Cardiovascular Surgery, Oita University Hospital, Oita, Japan.
Article Synopsis
- A 74-year-old man developed a giant myxoma in his right atrium three years after undergoing catheter ablation for an unspecified condition.
- The tumor was initially suspected to be malignant based on imaging studies but was later confirmed as a myxoma after surgical removal and pathological analysis.
- This case adds to existing reports that suggest a possible link between catheter ablation and the formation of cardiac myxomas due to tissue injury.
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