A case of left cerebellar intraparenchymal schwannoma in an adult is being presented along with ten available reports in the literature, differential diagnosis and management of the condition.
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Objective: We aim to provide a pictorial representation of the broad spectrum of intracranial hemorrhages associated with cerebral venous thrombosis (CVT), emphasizing atypical locations and rare intracerebral hemorrhage (ICH) types. We also hypothesize the pathophysiology leading to atypical locations of the ICH in CVT and the outcomes with anticoagulation therapy.
Background: ICH complicates about 40% of cases with CVT and is known to cause various types of ICH, including subarachnoid hemorrhage (SAH) and subdural hemorrhage (SDH).
Neuroimaging Spectrum of Erdheim-Chester Disease: An Image-based Review.
AJNR Am J Neuroradiol
November 2024
From the (1) Department of Radiology, Tata Memorial Hospital, Parel, Mumbai 400012 (P.R.), (2) Department of Radiology, Mayo Clinic, Rochester, MN (H.J.S, J.C.B, S.A.M, P.J.F, C.M.C, G.B.), and (3) Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 55902 (N.S., A.A), and The authors have no relevant disclosures of interest.
Erdheim-Chester Disease (ECD) is a rare, multisystem histiocytic disorder characterized by its variable clinical presentations. Central Nervous System (CNS) involvement is observed in approximately half of ECD patients (up to 76% in some series), and often carries a poorer prognosis. While CNS involvement may remain asymptomatic, others may experience a range of neurological symptoms, including cognitive decline, neuropsychiatric disturbances, motor deficits, cranial or peripheral neuropathies, and endocrine abnormalities.
View Article and Find Full Text PDFPediatric CNS-isolated hemophagocytic lymphohistiocytosis with brain hemorrhages: a case report.
BMC Neurol
October 2024
Division of Pediatric Hematology, Oncology, and Cellular Therapy, Nemours Children's Hospital, Wilmington, Delaware, USA.
Article Synopsis
- Hemophagocytic lymphohistiocytosis (HLH) is a rare immune disorder, and this case presents a unique instance of it affecting the central nervous system (CNS) in a pediatric patient.
- A 15-year-old boy exhibited symptoms like ataxia and MRI findings of multiple brain hemorrhages, which led to a confirmed diagnosis of familial CNS-HLH through genetic testing.
- After failing initial treatments, he underwent stem cell transplantation and showed significant improvement, underlining the importance of considering CNS-HLH in similar cases to avoid delays in diagnosis and treatment.
Metastatic prostate adenocarcinoma to the brain - a clinicopathologic analysis of 21 cases.
Diagn Pathol
October 2024
Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, USA.
Article Synopsis
- Brain metastasis from prostate adenocarcinoma (PCa) is uncommon but often leads to a poor prognosis, necessitating an assessment of its clinical and histopathological features for better diagnosis.
- A study reviewed 21 cases from the past 20 years, discovering that the average age for brain metastasis presentation was 70, with diverse types and locations of lesions.
- The research highlighted various histological patterns in tumor cells, including cribriform and papillary structures, and noted that nearly half of the cases displayed necrosis, indicating the need for thorough evaluation to improve diagnostic accuracy.
Ventricular system-unrelated cerebellar ependymoma: A case report.
World J Clin Cases
September 2024
Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China.
Background: An ependymoma is a glial tumor that usually occurs in or near the ventricle, close to the ependyma. It rarely occurs exclusively in the brain parenchyma without being associated with the ventricle.
Case Summary: Here, we report a rare case of a cerebellar ependymoma completely located in the brain parenchyma.
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