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Adipose-derived stem cell conditioned medium for hair regeneration therapy in alopecia: a review of literature.
Arch Dermatol Res
August 2024
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
To date, therapeutic choices for alopecia have shown limited effectiveness and safety, making the discovery of new therapeutic choices challenging. Adipose-derived stem cells conditioned-medium (ADSC-CM) contain various growth factors released by ADSCs that may support hair regrowth. This literature review aims to discover the effect and clinical impact of ADSC-CM in the treatment of alopecia.
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- The study aimed to create a new prognostic model to estimate the risk of pulmonary complications after elective surgery, which is the leading cause of post-surgery death.
- Data from a large international cohort of over 86,000 patients was used, applying machine learning techniques to identify risk factors for complications like pneumonia and respiratory distress.
- The model, named the GSU-Pulmonary Score, was validated with additional cohorts and is available as an online tool to assist in patient care and resource management, especially important during pandemic recovery.
Don't be deceived: bald-faced lies deceitful assertions.
Synthese
May 2023
Faculty of Philosophy, University of Warsaw, Krakowskie Przedmiescie 3, 00-927 Warsaw, Poland.
The traditional conception of lying, according to which to lie is to make an assertion with an intention to deceive the hearer, has recently been put under pressure by the phenomenon of bald-faced lies i.e. utterances that look like lies but because of their blatancy allegedly lack the accompanying intention to deceive.
View Article and Find Full Text PDFCharacterization of bird formations using fuzzy modelling.
J R Soc Interface
February 2023
Department of Environmental Sciences, Informatics and Statistics, Ca' Foscari University of Venice, 30123 Venezia, Italy.
The investigation of the emergent collective behaviour in flying birds is a challenging task, yet it has always fascinated scientists from different disciplines. In the attempt of studying and modelling line formation, we collected high-precision position data of 29 free-flying northern bald ibises () using Global Navigation Satellite System loggers, to investigate whether the spatial relationships within a flock can be explained by birds maintaining energetically advantageous positions. Specifically, we exploited domain knowledge and available literature information to model by means of fuzzy logic where the air vortices lie behind a flying bird.
View Article and Find Full Text PDFTowards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).
Biochem Soc Trans
June 2020
Cell Ageing Laboratory, Skin Research Institute of Singapore, 8A Biomedical Grove, #06-06 Immunos, 138648 Singapore.
The metazoan nucleus is equipped with a meshwork of intermediate filament proteins called the A- and B-type lamins. Lamins lie beneath the inner nuclear membrane and serve as a nexus to maintain the architectural integrity of the nucleus, chromatin organization, DNA repair and replication and to regulate nucleocytoplasmic transport. Perturbations or mutations in various components of the nuclear lamina result in a large spectrum of human diseases collectively called laminopathies.
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