Background: Infectious mononucleosis is usually a self-limiting illness, but can be rarely associated with complications.
Case Characteristics: A 17-year-old boy with Epstein-Barr virus related infectious mononucleosis and cold antibody-mediated autoimmune hemolytic anemia with incidentally noted multiple pulmonary nodules.
Observations: Nodules regressed over the next few weeks without specific therapy.
Message: Pediatricians need to be aware of this rare clinical presentation of infectious mononucleosis so that further invasive testing can be avoided.
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