Squamous cell carcinoma (SCC) has been commonly reported by foot and ankle specialists. Marjolin's ulcer is a malignancy that involves a posttraumatic scar or ulceration that can develop into SCC from chronic neuropathic pedal wounds, venous stasis, or decubitus ulcerations. Most Marjolin's ulcers are found in the lower extremity, specifically the feet, and it is twice as common in females as males. Biopsy of the tumor is the reference standard to diagnose SCC, and wide excision of SCC is the most common treatment option. The present case study describes an 83-year-old diabetic wheelchair-bound female who presented to the wound care clinic with a right heel nonhealing pressure ulceration. After biopsy and surgical excision, the patient was found to have SCC. This case was followed up for 5 years in which the patient had successful excision of the tumor with no recurrence. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of patients with SCC. In addition, this study has shown that adequate excision of the tumor margins and depth is necessary to prevent potential recurrence and metastasis.
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http://dx.doi.org/10.1053/j.jfas.2017.11.016 | DOI Listing |
ACS Biomater Sci Eng
January 2025
Advanced Materials Department, Jožef Stefan Institute, 1000 Ljubljana, Slovenia.
Characterization and formation of the biomineral aragonite structures of the Noah's Ark shell ( L.,1758) were studied from structural, morphogenetic, and biochemical points of view. Structural and morphological features were examined using X-ray diffraction, field-emission scanning electron microscopy, and atomic force microscopy, while thermal properties were determined by thermogravimetric and differential thermal analyses.
View Article and Find Full Text PDFN Engl J Med
January 2025
From the Departments of Medicine (D.R.) and Radiology (S.S.), Massachusetts General Hospital, the Departments of Medicine (D.R., S.D., J.A.S.) and Radiology (S.S.), Harvard Medical School, and the Department of Medicine, Brigham and Women's Hospital (S.D., J.A.S.) - all in Boston.
N Engl J Med
January 2025
Baylor College of Medicine, Houston, TX
Rev Soc Bras Med Trop
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Universidade Federal do Paraná, Departamento de Clínica Médica, Programa de pós-graduação em Medicina Interna e Ciências da Saúde, Curitiba, PR, Brasil.
Cryptococcal disease is the third most common invasive fungal infection in solid organ transplant recipients and is associated with high-morbidity and -mortality rates. Donor-derived Cryptococcus spp. infection typically manifests within the first month post-procedure and has historically been caused by C.
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