Background: Persistent right umbilical vein (PRUV) is usually an isolated finding but it may be accompanied by other fetal malformations.
Aims: We aimed to determine the incidence of prenatally diagnosed PRUV in a referral population, assess the neonatal outcome and discuss the findings together with those from previous publications.
Materials And Methods: A total of 2360 women with low-risk singleton pregnancies were examined in the second and third trimesters. A transabdominal convex volume transducer was used. B-mode was applied in each patient. Scanning of the venous system included imaging of the target vessels with two-dimensional colour Doppler mapping. The diagnosis of PRUV was made in a transverse section of the fetal abdomen. Three-dimensional ultrasounds were performed as necessary, when anomalous cases were encountered.
Results: The incidence of PRUV in our population was 12/2360 = 0.5%, and it was higher than in other retrospective studies. In 75% (n = 9), PRUV was an isolated finding where delivery was uneventful and the postnatal outcome was favourable. In two cases PRUV was accompanied by omphalocele, and in one case by tetralogy of Fallot and single umbilical artery.
Conclusions: PRUV is an uncommon prenatal finding. Screening for this anomaly can be easily performed in all pregnant patients. A diagnosis of PRUV should be followed by a thorough fetal morphology scan in order to exclude any other malformations, especially those of the cardiovascular system.
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http://dx.doi.org/10.1111/ajo.12791 | DOI Listing |
Ann Pediatr Cardiol
November 2024
Department of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India.
Background: The ductus venosus (DV) is a pivotal component of fetal circulation. Absent DV (ADV) is associated with structural defects, portal vein (PV) anomalies, and chromosomal anomalies. This observational study aims to investigate the impact of ADV on fetal circulation and postnatal outcomes.
View Article and Find Full Text PDFStem Cell Res Ther
December 2024
State Key Laboratory of Membrane Biology, School of Basic Medical Sciencese, Institute of Precision Medicine, Tsinghua University, Beijing, 100084, China.
Background: Idiopathic Pulmonary Fibrosis (IPF) is a type of interstitial lung disease characterized by chronic inflammation due to persistent lung damage. Mesenchymal stem cells (MSCs), including those derived from the umbilical cord (UCMSCs) and placenta (PLMSCs), have been utilized in clinical trials for IPF treatment. However, the varying therapeutic effectiveness between these two MSC types remains unclear.
View Article and Find Full Text PDFBMC Infect Dis
December 2024
Department of Infectious Diseases, the Third People's Hospital of Chengdu, Chengdu, Sichuan, 610031, China.
To enhance the current clinical understanding and improve the diagnosis and treatment of Actinotignum schaalii infections, we have presented here a report of the case of recurrent infections at a periumbilical scar, induced by Actinotignum schaalii and complicated by abscess formation in a 50-year-old woman with persistent festering at the site of a periumbilical scar after laparoscopy 9 years ago, with subsequent ruptures over the past 2 years. Physical examination revealed a radial fold scar with localized redness and slight swelling of the skin below the navel. Although no significant increase in the local skin temperature was noted, tenderness was present.
View Article and Find Full Text PDFSurg Radiol Anat
December 2024
Department of Plastic Surgery, Iida Municipal Hospital, Iida, Japan.
Purpose: This study aimed to investigate the relationship between linea alba width and unclosed pediatric umbilical hernias.
Methods: A retrospective chart review was conducted on patients with pediatric umbilical hernias persisting beyond the age of 2, from April 2014 to March 2021. Additionally, data from children who underwent computed tomography (CT) for other conditions or injuries, such as diarrhea or traffic accidents, were collected from April 2010 to March 2022.
J Oral Biol Craniofac Res
November 2024
Healthcare and Research, Irvine Medical Center, University of California, Irvine, United States.
Background: Previous studies revealed diabetes mellitus subjects tend to have persistent apical periodontitis. Regenerative stem cells therapy through endodontic procedure is hoped to be a solution. This study assessed bone regeneration in diabetic rats with apical periodontitis through histopathological analysis of osteoblasts and immunohistochemical analysis of runt-related transcription factor 2 (Runx2) and Osterix.
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