Myosin-Driven Intracellular Transport.

Cold Spring Harb Perspect Biol

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.

Published: March 2018

The delivery of intracellular material within cells is crucial for maintaining normal function. Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein particles (RNPs), in plants, fungi, and metazoa. The properties of a given myosin transporter are adapted to move on different actin filament tracks, either on the disordered actin networks at the cell cortex or along highly organized actin bundles to distribute their cargo in a localized manner or move it across long distances in the cell. Transport is controlled by selective recruitment of the myosin to its cargo that also plays a role in activation of the motor.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830894PMC
http://dx.doi.org/10.1101/cshperspect.a021972DOI Listing

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