Solvent-Detergent Plasma for the Treatment of Thrombotic Microangiopathies: A Canadian Tertiary Care Centre Experience.

Transfus Apher Sci

Division of Hematology, Department of Medicine, Vancouver General Hospital, 10(th) Floor, 2775 Laurel Street, V5Z1M9, Vancouver, BC, Canada. Electronic address:

Published: April 2018

Solvent detergent-treated plasma (SDP) is a pathogen-inactivated blood plasma, which in comparison to frozen plasma is associated with lower rates of allergic reaction, transfusion-associated lung injury, and viral transmission. SDP has been available in Canada since 2012. Data on SDP use in Canada remains limited. We present a review of subjects receiving SDP at a large tertiary care centre primarily for thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, demonstrating the tolerability and safety of SDP.

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http://dx.doi.org/10.1016/j.transci.2018.02.005DOI Listing

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