AI Article Synopsis

  • * Methods: Researchers conducted a retrospective analysis of cytological reports from 332 patients at a specialized cancer institute over four years, focusing on various anatomical sites like lymph nodes, thyroid, and breast.
  • * Results: FNCC demonstrated very high diagnostic accuracy with a sensitivity of 99.55% and specificity of 98.77%, proving it to be a safe, reliable, and cost-effective method for diagnosing tumors with minimal complications.

Article Abstract

Objective: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours.

Material And Methods: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016.

Results: A total of 332 patients were selected, with an average age of 54.77 years (range 13-90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%.

Conclusions: FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828675PMC
http://dx.doi.org/10.3332/ecancer.2018.805DOI Listing

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