We report for the first time, to the best of our knowledge, an all-fiber Raman graded-index (GRIN) fiber laser pumped by a fiber laser. This configuration points to potential future power and brightness increases. Continuous-wave power of 135 W with an M value of 2.5 was obtained at a wavelength of 1081 nm with an optical-to-optical efficiency of 68%. A commercial GRIN core fiber acts as the Raman fiber in a power oscillator configuration that includes fiber Bragg gratings (FBGs) written onto the GRIN fiber. The efficiency and brightness demonstrated here are, to the best of our knowledge, the highest reported in any Raman GRIN fiber laser. A brightness enhancement of the pump beam by a factor of 5.6 is attained due to the transverse profiles of Raman gain and FBG reflection in the GRIN fiber.
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http://dx.doi.org/10.1364/OL.43.001027 | DOI Listing |
Toxins (Basel)
November 2024
Institut des Neurosciences Paris-Saclay, UMR 9197, CNRS/Université Paris-Sud, 91198 Gif-sur-Yvette, Cedex, France.
Botulinum neurotoxin type-A (BoNT/A), which blocks quantal acetylcholine (ACh) release at the neuromuscular junction (NMJ), has demonstrated its efficacy in the symptomatic treatment of blepharospasm. In 3.89% of patients treated for blepharospasm at Tenon Hospital, BoNT/A was no longer effective in relieving the patient's symptoms, and a partial upper myectomy of the muscle was performed.
View Article and Find Full Text PDFBiosensors (Basel)
December 2024
Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), Shenzhen 518107, China.
The demand for non-invasive, real-time health monitoring has driven advancements in wearable sensors for tracking biomarkers in sweat. Ammonium ions (NH) in sweat serve as indicators of metabolic function, muscle fatigue, and kidney health. Although current ion-selective all-solid-state printed sensors based on nanocomposites typically exhibit good sensitivity (~50 mV/log [NH]), low detection limits (LOD ranging from 10 to 10 M), and wide linearity ranges (from 10 to 10 M), few have reported the stability test results necessary for their integration into commercial products for future practical applications.
View Article and Find Full Text PDFAm J Physiol Cell Physiol
December 2024
Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Plasma membrane repair (PMR) restores membrane integrity of cells, preventing cell death in vital organs, and has been studied extensively in skeletal muscle. Dysferlin, a sarcolemmal Ca-binding protein, plays a crucial role in PMR in skeletal muscle. Previous studies have suggested that PMR employs membrane trafficking and membrane fusion, similar to neurotransmission.
View Article and Find Full Text PDFUrology
December 2024
Division of Urology, Department of Surgery, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Objectives: To investigate the effectiveness of different holmium:yttrium-aluminum-garnet (Ho:YAG) laser modes for lithotripsy in the "dusting era" and identify the optimal laser mode for producing stone fragments measuring ≤0.5 mm.
Methods: We used plaster of Paris-made artificial stones crushed into 2-3 mm pieces, weighing 1 g in total.
J Cancer Res Clin Oncol
December 2024
Department of Neurosurgery, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Purpose: Analysis of autofluorescence holds promise for brain tumor delineation and diagnosis. Therefore, we investigated the potential of a commercial confocal laser scanning endomicroscopy (CLE) system for clinical imaging of brain tumors.
Methods: A clinical CLE system with fiber probe and 488 nm laser excitation was used to acquire images of tissue autofluorescence.
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