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Examining the impacts of natural and anthropogenic influences on aquatic macrophytes in shallow lakes is crucial for their effective restoration and management. However, there is a lack of direct evidence regarding past species composition or detailed and continuous evidence of recent changes in aquatic macrophyte communities. This study utilized plant macrofossil remains deposited in the sediment, combined with macrophyte surveys from 1983 to 2010, to reconstruct the historical changes in the macrophyte community over approximately 160 years in Lake Weishan, a sub-lake of Lake Nansi located in the lower Yellow River (Huanghe River) Basin, northern China.
View Article and Find Full Text PDFApplication and development of CRISPR technology in the secondary metabolic pathway of the active ingredients of phytopharmaceuticals.
Front Plant Sci
January 2025
College of Life Sciences, Northwest Agricultural and Forestry University, Yangling, Shaanxi, China.
As an efficient gene editing tool, the CRISPR/Cas9 system has been widely employed to investigate and regulate the biosynthetic pathways of active ingredients in medicinal plants. CRISPR technology holds significant potential for enhancing both the yield and quality of active ingredients in medicinal plants. By precisely regulating the expression of key enzymes and transcription factors, CRISPR technology not only deepens our understanding of secondary metabolic pathways in medicinal plants but also opens new avenues for drug development and the modernization of traditional Chinese medicine.
View Article and Find Full Text PDFLong-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture system.
Front Microbiol
January 2025
College of Agriculture, Shandong Agricultural University/National Key Laboratory of Wheat Improvement, Taian, China.
Continuous monocropping of peanuts (.) often results in yield decline and soil degradation. The combination of green manure (GM) with tillage practices has been proposed as a sustainable strategy to maintain high crop productivity and improve soil quality.
View Article and Find Full Text PDFMixed lipopeptide-based mucosal vaccine candidate induces cross-variant immunity and protects against SARS-CoV-2 infection in hamsters.
Immunohorizons
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Department of Surgery, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, AB, Canada.
The global dissemination of SARS-CoV-2 led to a worldwide pandemic in March 2020. Even after the official downgrading of the COVID-19 pandemic, infection with SARS-CoV-2 variants continues. The rapid development and deployment of SARS-CoV-2 vaccines helped to mitigate the pandemic to a great extent.
View Article and Find Full Text PDFLong-term impact of COVID-19-related nonpharmaceutical interventions on tuberculosis: an interrupted time series analysis using Bayesian method.
J Glob Health
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Beijing Key Laboratory of Antimicrobial Agents/Laboratory of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: The implementation of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic may inadvertently influence the epidemiology of tuberculosis (TB). (TB). However, few studies have explored how NPIs impact the long-term epidemiological trends of TB.
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