[This corrects the article DOI: 10.1186/s40900-017-0075-x.].
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http://dx.doi.org/10.1186/s40900-018-0090-6 | DOI Listing |
Se Pu
February 2025
Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai 200237, China.
Thromboxane A (TXA), a prothrombotic factor that induces platelet aggregation and thrombosis, acts as a vasoconstrictor by activating TXA receptors (TP receptors). TXA is extremely unstable and metabolizes into three major metabolites: 2,3-dinor thromboxane B (2,3-dinor-TXB), 11-dehydro TXB(11-dh-TXB), and 11-dehydro-2,3-dinor TXB(11-dh-2,3-dinor-TXB). 8-Iso-prostaglandin F(8-iso-PGF), a prostaglandin-like compound widely considered the best biomarker of oxidative stress, can also activate TP receptors.
View Article and Find Full Text PDFZhonghua Er Ke Za Zhi
January 2025
Department of Emergency, Xi'an Children's Hospital, Xi'an710003, China.
To explore clinical and genetic features of persistent asymptomatic microscopic hematuria in children. A retrospective case analysis of 135 individuals admitted to Xi 'an Children's Hospital with persistent asymptomatic microscopic haematuria between January 2016 to December 2023 was conducted. The demographic characteristics, kidney pathology and gene results of 135 individuals were analyzed.
View Article and Find Full Text PDFBMC Nurs
January 2025
Centro de Investigação, Inovação e Desenvolvimento em Enfermagem de Lisboa, Egas Moniz School of Health&Science, Lisboa, Portugal.
Background: The highly technological environment existing in intensive care units, essential for the survival of the newborn, contributes with a potentially devastating and traumatic effect, especially in preterm newborns and in their future lives, due to the early and frequent exposure to multiple stressors. The preterm newborn must be observed in a systematic and structured way, before, during and after any intervention, aiming at the correct assessment and interpretation of his behaviour and signs of stress, and at the timely planning of interventions that minimize and prevent stress. The objective of this review is to identify and map the instruments for assessing stress in preterm newborns admitted to neonatal units in scientific evidence.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
Department of Otorhinolaryngology Head and Neck Surgery, Linyi People's Hospital Affiliated to Shandong Second Medical University, Linyi276003, China.
To explore the surgical methods and treatment outcomes of nasal endoscopic surgery for nasal deformity secondary to unilateral cleft lip and palate, combined with nasal septal deviation, using nasal septal cartilage and bone. Eleven patients who underwent surgical treatment for unilateral cleft lip and palate secondary to nasal deformity in the Department of Otorhinolaryngology, Head and Neck Surgery, Linyi People's Hospital, Shandong Second Medical University, from March 2021 to March 2023, were retrospectively analyzed. The cohort included 8 males and 3 females, aged (22.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
Department of Laboratory, Wenzhou People's Hospital, Wenzhou Third Clinical College of Wenzhou Medical University, Wenzhou Maternal and Child Health Hospital, Wenzhou325027, China.
To investigate the feasibility of prime editor (PE) and adenine base editor (ABE) for correction the pathogenic variant of the human deafness gene c.1229C>T. From March 2023 to April 2024, prime editing guide RNA (pegRNA) expression vectors as well as single guide RNA (sgRNA) were designed and constructed for the c.
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