Background: Endovascular treatment is an alternative first-line management for peripheral artery disease (PAD). Hybrid treatment (HT) is defined as a combined treatment for patients with PAD using endovascular and open surgery, simultaneously performed in an operating room. The results of HT are reportedly good for multilevel revascularization (MR) in patients with chronic limb ischaemia, and even in older high-risk patients. The goal of this study was to examine the clinical and haemodynamic outcomes of HT in patients who need MR.
Patients And Methods: Nine university hospitals in Korea participated in this multicentre study. A total of 134 patients with multilevel PAD underwent HT and MR. Patients were enrolled from July 2014 to June 2015 and were followed for 18 months.
Results: The mean age of the patients was 68.8 ± 9.93 years and 88.1 % were men. Patients with Rutherford category 2 to 3 and 4 to 6 comprised 59.0 % and 42.0 % of the group, respectively. The technical success rate was 100 %. The primary patency rates at 12 and 18 months were 77.6 % and 63.9 %, respectively. The primary-assisted patency rates at 12 and 18 months were both 90.0 %. The pre-operative mean ankle brachial index (0.43 ± 0.23) increased to 0.87 ± 0.23 at six months post-operatively (t-test, p < 0.05). The amputation free survival rate was 97.1 %.
Conclusions: Although outcomes of multilevel PAD are reportedly poor when endovascular treatment alone is used, we have shown that HT is a feasible alternative modality for patients with multilevel PAD, with satisfactory amputation-free survival and freedom from re-intervention rates.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1024/0301-1526/a000694 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The nanocellulose fiber scaffold to construct a hierarchical phenolic coating on cotton fiber surfaces for inactivating pathogens through an enhanced protein adsorption mechanism.
Carbohydr Polym
January 2025
School of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, China; Zhejiang Provincial Innovation Center of Advanced Textile Technology, 700 Yuhui Road, Keqiao Distrit, Shaoxing 312030, China. Electronic address:
Emerging pathogens present a significant societal threat, and biological protection textiles are expected to play a pivotal role in controlling their spread. However, incorporating highly effective pathogen transmission-blocking abilities into textiles while ensuring their large-scale production remains challenging. This work has successfully developed a hierarchically structured coating for cotton fibers, which exhibits enhanced antiviral and antibacterial functionalities compared to existing phenolic coating methods.
View Article and Find Full Text PDFComplex Peripheral Arterial Disease in a Case of Multilevel Lesions Treated With Sequential Angioplasty.
Cureus
May 2024
General Internal Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Peripheral artery disease (PAD) is the buildup of calcium and fatty deposits in the arterial walls (atherosclerosis). This is an important clinical issue, specifically in cases with multilevel lesions. A patient underwent sequential angioplasty treatment for major PAD, which was characterized by multilevel lesions affecting both the infrapopliteal arteries.
View Article and Find Full Text PDFComparison between intermittent claudication chronic limb-threatening ischemia in peripheral arterial disease: a retrospective multicenter cohort study.
Ann Surg Treat Res
June 2024
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Article Synopsis
- * Researchers analyzed data from 506 patients who received endovascular treatment, finding that CLTI patients had more diabetes and severe disease, while IC patients had more aortoiliac lesions and procedures like atherectomies.
- * CLTI patients experienced worse outcomes, including lower rates of primary patency and higher rates of amputation and mortality compared to those with IC, indicating the need for tailored treatment approaches.
Impact of early intervention on health status outcomes in peripheral artery disease patients with chronic total occlusion lesions using the PORTRAIT registry.
J Vasc Surg
September 2024
Vascular Medicine Outcomes (VAMOS) Program, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT. Electronic address:
Objective: To analyze the impact of noninvasive and early invasive treatments on health status in patients with lower extremity peripheral arterial disease (PAD) without and with chronic total occlusions (CTOs) after 12 months of follow-up.
Methods: Using the international (the United States, the Netherlands, and Australia) observational longitudinal Patient-Centered Outcomes Related to Treatment Practices in Peripheral Arterial Disease: Investigating Trajectories registry, we included patients with recent PAD symptoms between June 2011 and December 2015. We assessed the PAD-specific health status at initial visit and the 3-, 6-, and 12-month follow-up using the Peripheral Arterial Questionnaire.
Shared decision-making needs, barriers, and facilitators of patients with newly diagnosed advanced cancer in the hospital: a multi-level, mixed-methods study.
Support Care Cancer
April 2024
Department of Medicine, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Article Synopsis
- Patients with advanced cancer in the hospital really need help making decisions about their treatment because they often feel confused and unsure.
- The study looked at what patients, caregivers, and doctors think about decision-making and found that there are many challenges, like not having enough information.
- Doctors also said patients don't always know what to expect after leaving the hospital, so it’s important to find ways to help them understand their choices better.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!