A method for evaluating reactive postischemic hyperemia on the skin using the laser Doppler velocimeter is described. The study was conducted on healthy subjects and on patients affected by chronic occlusive arterial disease of the lower limbs at the second clinical stage. The laser Doppler probe is applied to the pulp of the hallux and the inflatable cuff is used for the transient occlusion of arteries both around the thigh and around the ankle. The data obtained are significant for differences between patients and controls and suggest that the cutaneous postischemic hyperemia test is of diagnostic value. The test may be used both for screening and in the follow-up of the peripheral occlusive arterial disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0026-2862(86)90066-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Circadian and sex differences in post-ischemic vasodilation and reactive hyperemia in young individuals and elderly with and without type 2 diabetes.
Microcirculation
August 2023
Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.
Objective: Cardiovascular events show morning preference and sex differences, and are related to aging and type 2 diabetes. We assessed circadian variations and sex differences in vascular conductance (VC) and blood flow (BF) regulations following a brief bout of forearm ischemia.
Methods: Young healthy individuals (H18-30) and elderly without (H50-80) and with type 2 diabetes (T2DM50-80) of both sexes were included.
Monitoring Muscle Perfusion in Rodents During Short-Term Ischemia Using Power Doppler Ultrasound.
Ultrasound Med Biol
June 2023
Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Electronic address:
Objective: The aim of this work was to evaluate the reliability of power Doppler ultrasound (PD-US) measurements made without contrast enhancement to monitor temporal changes in peripheral blood perfusion.
Methods: On the basis of pre-clinical rodent studies, we found that combinations of spatial registration and clutter filtering techniques applied to PD-US signals reproducibly tracked blood perfusion in skeletal muscle. Perfusion is monitored while modulating hindlimb blood flow.
Post-ischemic hyperemia following endovascular therapy for acute stroke is associated with lesion growth.
J Cereb Blood Flow Metab
June 2023
NIH/NINDS, Stroke Branch, Bethesda, MD, USA.
A substantial proportion of acute stroke patients fail to recover following successful endovascular therapy (EVT) and injury to the brain and vasculature secondary to reperfusion may be a contributor. Acute stroke patients were included with: i) large vessel occlusion of the anterior circulation, ii) successful recanalization, and iii) evaluable MRI early after EVT. Presence of hyperemia on MRI perfusion was assessed by consensus using a modified ASPECTS.
View Article and Find Full Text PDFA novel operator-independent noninvasive device for assessing arterial reactivity.
Int J Cardiol Heart Vasc
April 2022
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Background: Endothelial dysfunction is associated with increased risk of cardiovascular disease (CVD). Currently available noninvasive methods of measuring endothelial function have limitations. We tested a novel device that provides an automated measurement of the difference between baseline and post-ischemic, hyperemia-induced, brachial arterial compliance, a phenomenon known to be endothelium-dependent.
View Article and Find Full Text PDFChronic Low-Dose Alcohol Consumption Promotes Cerebral Angiogenesis in Mice.
Front Cardiovasc Med
November 2021
Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States.
Chronic alcohol consumption dose-dependently affects the incidence and prognosis of ischemic stroke. We determined the influence of chronic alcohol consumption on cerebral angiogenesis under physiological conditions and following ischemic stroke. In studies, acute exposure to low-concentration ethanol significantly increased angiogenic capability and upregulated vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor 2 (VEGFR2) in C57BL/6J mouse brain microvascular endothelial cells (MBMVECs).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!