The circulatory effects of enflurane (Ethrane) were studied in 10 unmedicated volunteers during anesthesia over a period of 90 min or more. Cardiac output did not change significantly at a mean alveolar concentration of 2.3 vol.%. Heart rate was increased in all cases. Enflurane causes negative inotropic activity in the heart muscle but has little influence on the pump performance of the heart.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1399-6576.1979.tb05477.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exposure to halogenated ethers causes neurodegeneration and behavioural changes in young healthy experimental animals: a systematic review and meta analyses.
Sci Rep
May 2023
Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Geert Grooteplein-Noord 21, route 126, 6525 GA, Nijmegen, The Netherlands.
The FDA issued a warning that repeated and prolonged use of inhalational anaesthetics in children younger than 3 years may increase the risk of neurological damage. Robust clinical evidence supporting this warning is however lacking. A systematic review of all preclinical evidence concerning isoflurane, sevoflurane, desflurane and enflurane exposure in young experimental animals on neurodegeneration and behaviour may elucidate how severe this risk actually is PubMed and Embase were comprehensively searched on November 23, 2022.
View Article and Find Full Text PDF[Health hazards resulting from occupational exposure to enfluran - overview of tests and analysis of admissible concentration values].
Med Pr
February 2022
Instytut Medycyny Pracy im. prof. J. Nofera / Nofer Institute of Occupational Medicine, Łódź, Poland (Zakład Bezpieczeństwa Chemicznego / Department of Chemical Safety).
The aim of this work is to analyze the health hazards of enflurane exposure and to analyze the occupational exposure limits (OEL). The method of obtaining evidence based on a review of online databases of scientific journals was used. Enflurane is an inhalation anesthetic.
View Article and Find Full Text PDFAppraisal and development of evidence-based clinical decision support to enable perioperative pharmacogenomic application.
Pharmacogenomics J
December 2021
Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, IL, USA.
Variable responses to medications complicates perioperative care. As a potential solution, we evaluated and synthesized pharmacogenomic evidence that may inform anesthesia and pain prescribing to identify clinically actionable drug/gene pairs. Clinical decision-support (CDS) summaries were developed and were evaluated using Appraisal of Guidelines for Research and Evaluation (AGREE) II.
View Article and Find Full Text PDFEffect of anesthesia on electrocorticography for localization of epileptic focus: Literature review and future directions.
Epilepsy Behav
May 2021
Comprehensive Epilepsy Center, Dept. of Neurology, School of Medicine, Yale University, Yale New Haven Hospital, New Haven, CT, United States; Human Brain Mapping Program, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Intraoperative electrocorticography (ECoG) is a useful technique to guide resections in epilepsy surgery and is mostly performed under general anesthesia. In this systematic literature review, we seek to investigate the effect of anesthetic agents on the quality and reliability of ECoG for localization of the epileptic focus. We conducted a systematic search using PubMed and EMBASE until January 2019, aiming to review the effects of anesthesia on ECoG yield.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!