AI Article Synopsis
- The use of assisted reproductive technologies (ART) has more failures than successes, prompting research into perifollicular blood flow (PFBF) as a possible predictor of outcomes.
- A systematic review of studies found that measuring PFBF may correlate with better oocyte and embryo quality, particularly improving pregnancy rates after IVF/ICSI, but not with IUI outcomes.
- There is a call for further randomized controlled trials to explore the potential prognostic value of PFBF assessment in ART.
Article Abstract
Background: The overall final outcome of assisted reproductive technologies (ART) is still more often a failure than a success. Assessing perifollicular blood flow (PFBF) is one technique to predict and possibly improve this outcome. The aim was to provide a structured review of studies concerning PFBF and its prognostic value in patients undergoing ART, including IUI (intrauterine insemination).
Methods: PUBMED, EMBASE and Cochrane Database of Systematic Reviews were searched for relevant studies published until December 2016. As key words 'Perifollicular blood flow', 'IUI', 'IVF' and 'ICSI' were used.
Results: A total of 14 articles were included in the current review. The results are very heterogeneous, though there is evidence that measuring PFBF could be a good prognostic marker for oocyte and embryo quality, but even more for pregnancy rate after IVF/ICSI. This finding is not observed in studies concerning IUI.
Conclusions: Our results highlight an urgent need to investigate the role for PFBF assessment by Power Doppler in ART in randomised controlled trials.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819322 | PMC |
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