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http://dx.doi.org/10.1038/nphoton.2016.141 | DOI Listing |
J Neural Eng
December 2024
Stanford University, 452 Lomita Mall, Stanford, California, 94305, UNITED STATES.
Objective: Neural interfaces are designed to evoke specific patterns of electrical activity in populations of neurons by stimulating with many electrodes. However, currents passed simultaneously through multiple electrodes often combine nonlinearly to drive neural responses, making evoked responses difficult to predict and control. This response nonlinearity could arise from the interaction of many excitable sites in each cell, any of which can produce a spike.
View Article and Find Full Text PDFBiomed Opt Express
December 2024
Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Retinal pigment epithelium (RPE) cells are essential for normal retinal function. Morphological defects in these cells are associated with a number of retinal neurodegenerative diseases. Owing to the cellular resolution and depth-sectioning capabilities, individual RPE cells can be visualized in vivo with adaptive optics-optical coherence tomography (AO-OCT).
View Article and Find Full Text PDFNat Commun
November 2024
School of Optometry, Indiana University, Bloomington, IN, USA.
Adaptive optics (AO) is a powerful method for correcting dynamic aberrations in numerous applications. When applied to the eye, it enables cellular-resolution retinal imaging and enhanced visual performance and stimulation. Most ophthalmic AO systems correct dynamic aberrations up to 1-2 Hz, the commonly-known cutoff frequency for correcting ocular aberrations.
View Article and Find Full Text PDFAdv Sci (Weinh)
November 2024
Department of Materials Science and Engineering, Stanford University, 350 Jane Stanford Way, Stanford, CA, 94305, USA.
Biomed Opt Express
November 2024
Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne 3010, Australia.
confocal microscopy (IVCM) is a widely used technique for imaging the cornea of the eye with a confocal scanning light ophthalmoscope. Cellular resolution and high contrast are achieved without invasive procedures, suiting the study of living humans. However, acquiring useful image data can be challenging due to the incessant motion of the eye, such that images are typically limited by noise and a restricted field of view.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!