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Increased DNMT1 acetylation leads to global DNA methylation suppression in follicular granulosa cells during reproductive aging in mammals.
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College of Animal Science and Technology, Hebei Agricultural University, Baoding, 071000, China.
With increasing age, the reproductive performance of women and female animals declines. However, the molecular mechanisms underlying ovarian aging and age-related fertility decline remain unclear. Granulosa cells (GCs) are suspected to play an important role in reproductive aging, and their proliferation, apoptosis, and steroid hormone secretion are used to determine the fate of follicles and ovarian function.
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McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas; Department of Ophthalmology and Visual Science, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas. Electronic address:
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National Center for Global Health, Istituto Superiore di Sanita, Rome, Italy.
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View Article and Find Full Text PDFCoadministration of Lactulose with Probiotics Ameliorates Loperamide-Induced Constipation in Mice.
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Department of Integrated Biomedical and Life Science, Graduate School, Korea University, Seoul 02841, Korea.
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